Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12N
MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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C12N2710/10311
Mastadenovirus, e.g. human or simian adenoviruses
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C12N2710/10341
Use of virus, viral particle or viral elements as a vector
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C12N2710/10344
Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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C12N2710/10344

COMPOSITIONS AND METHODS FOR SELECTIVE GENE REGULATION
20260078404 · 2026-03-19 ·

Provided herein are engineered transcription factors for selective upregulation of SCN1a and uses thereof for treating diseases and disorders, such as, Dravet syndrome. Also provided are microRNA binding sites and uses thereof for selective expression in parvalbumin neurons.