Provided herein are in vivo gelling ophthalmic pre-formulations forming a biocompatible retinal patch comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally a therapeutic agent and/or viscosity enhancer. In some embodiments, the retinal patch at least partially adheres to the site of a retinal tear. Also provided herein are methods of treating retinal detachment by delivering an in vivo gelling ophthalmic pre-formulation to the site of a retinal tear in human eye, wherein the in vivo gelling ophthalmic pre-formulation forms a retinal patch.

A fixture includes a first ring member and a second ring member. The first ring member has a first open center and has a first tool connector disposed at a first radial position relative to the first open center. The second ring member has a second open center coupled to the first ring member at a joint. The joint is disposed at a second radial position relative to the first open center. The joint has a second tool connector. The joint is configured to enable movement of the first ring member relative to the second ring member.

A device for prosthetic vision rehabilitation, which includes a scleral explant with a shape that is suitable for being in contact with at least one portion of the sclera of an eye, and at least one inducer arranged on the scleral explant.

Tissue manipulation during ocular surgery may be achieved by a variety of systems and techniques. In particular implementations, a system may include spaced apart levers, hinge members, a grasping mechanism, and a guide mechanism located between the levers. A first hinge member may extend from one of the levers to the guide mechanism and move the guide mechanism in one of a proximal or distal direction when the levers are moved toward each other. The grasping mechanism may be coupled to the guide mechanism and extend distally from the guide mechanism. A second hinge member may extend from one of the levers and be coupled to a tube that surrounds a portion of the grasping mechanism. The second hinge member distally displaces the tube when the levers are moved towards each other. The relative motion of the guide mechanism and the tube may cause actuation of the grasping mechanism.

A vitreoretinal surgery device includes a main body defining a receiving chamber therein and a needle or cannula provided with an inner longitudinal cavity in connection with said receiving chamber. The device includes a plurality of instruments, of which at least a first surgical instrument of elongated shape, and a second surgical instrument of elongated shape, and a selecting unit associated with the first and second surgical instruments, accommodated at least partially in said receiving chamber and configured to arrange the first surgical instrument in the operating position and the second surgical instrument in the resting position, or vice versa, upon a command given by a user.

A surgery system comprises a camera obtaining camera images, an OCT system, a data memory storing geometry data of a surgical tool 133 and a controller configured to identify a first portion of the tool in the camera images by object recognition using the geometry data; to determine, in the field of view, first locations where the tool is located and second locations aside of the tool; to trigger the OCT system to perform depth scans at the first and second locations; to identify a second portion 153 of the tool in the depth scans by object recognition using the geometry data; and to generate a first image 154 representing a third portion 157 of the tool based on the geometry data and the depth scans.

Described herein is an apparatus for treatment of an ocular condition of a patient, comprising a hollow elongate member sized to penetrate an eye of the patient and including a body portion, a distal tip, and a lumen extending though both. The body portion includes a proximal end, a distal end, and a first diameter, and defines longitudinal axis. The distal tip extends from the distal end of the body portion and is arranged to treat tissue in the eye. The distal tip includes an inner tube defining the lumen in part, an outer sheath surrounding the inner tube, and a second diameter. The distal tip is configured to transition between a first rigid orientation and a second less rigid orientation.

A treatment method is provided that includes an introduction step of introducing a transparent stent into a vitreous body of an eyeball, an expansion step of causing the stent to expansively deform inside the vitreous body to bring a retina into contact with a retinal pigment epithelium, and a placement step of placing the stent in the vitreous body with the stent keeping the retina in contact with the retinal pigment epithelium.

A cannula device for draining sub-retinal fluid externally to the eye includes a shaft, an outer sleeve, and an inner sleeve. The outer sleeve and the inner sleeve have a curve therein to access the back of the eye externally. The outer sleeve is extendable relative to the inner sleeve and the shaft, and the outer sleeve includes a penetrative tip to penetrate the sclera and provide access to the sub-retinal fluid to the inner sleeve.

The present disclosure describes systems and methods for selectively constraining an orientation of a portion of a surgical tool system relative to another. Example surgical tool systems may include a surgical tool having at least one movable component, at least one actuation component, and a surgical tool attachment. The surgical tool attachment may be operable selectively to engage and disengage the moveable component so as to prevent movement of the movable component relative to the surgical tool in an engaged configuration and to permit movement of the movable component relative to the surgical to in a disengaged configuration, respectively. In the engaged configuration, a dynamic component of the surgical tool system may be fixed relative to the surgical tool, and, in a disengaged configuration, the dynamic component may be freely movable relative to the surgical tool.