Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking.

Ophthalmic treatment systems and methods of using the systems are disclosed. The ophthalmic treatment systems include (a) a light source device; (b) at least one optical treatment head operatively coupled to the light source device, comprising a light source array, and providing at least one treatment light; and (c) a light control device, which (i) provides patterned or discontinuous treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye); or (ii) adjusts intensity of part or all of the light source array, providing adjusted intensity treatment light projection onto an eye (e.g., the cornea and/or sclera of an eye). The at least one treatment light promotes corneal and/or scleral collagen cross-linking.

Embodiments of this disclosure disclose an imaging system, including an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The beam source generates an electromagnetic radiation beam. The detection assembly generates a signal indicative of an intensity of a portion of the electromagnetic radiation beam reflected from the focal point location. A subsequent focal point of the electromagnetic radiation beam may be adjusted per the measured intensity signal. In some embodiments, an intensity signal below a lower threshold value may suggest a depth increase for a subsequent focal point. An intensity signal above an upper threshold value may suggest a depth decrease for a subsequent focal point. And, an intensity signal between the lower and upper thresholds may suggest a depth be maintained for a subsequent focal point. The focal point may be adjusted after each pulse or after a plurality of pulses.

A donor corneal tissue cutting blade provided with integrally formed asymmetrical markers for facilitation identification of the anterior and posterior sections or portions of the donor corneal tissue is disclosed. The blade is a cylindrical body having, in one embodiment, a U-shaped extension which cooperates with the body to define a keyway. Protrusions may be formed on the body and/or extension to provide further markers.

Provided herein is a single piece fixed depth trephine for use in ophthalmic surgeries and other surgical applications. Related methods are also described.

Precise concentric, symmetric, and repeatable circular scoring (cutting) of Descemet's membrane is made possible by a handheld surgical ophthalmic device. The precision of the cut is provided by a stabilizing point on a stabilizing arm as well the anchoring insertion point at the limbus. Stabilization through the insertion point and the stabilizing arm provides a two-point fixation thereby establishing a cutting plane. The cutting plane allows for precise depth of cut whereas the rotating blade's consistent radius allows for circularity of the cut. The stabilization arm fixates on tissue, and is then removed when the procedure is completed. Consistent torque and contact pressure of the cutting blade is provided through rotational control via the depression of a button on a handle thereby removing the need to “free-hand” the desemetorhexis.

A surgical cannulated blade instrument includes a blade portion having a pointed end, a top surface, and a bottom surface opposite the top surface, an increasing diameter portion having a diameter which increases in a direction away from the pointed end, and a cannula portion having a lumen opening at a location between the pointed end and the increasing diameter portion. An eye surgery method includes incising a cornea of an eye using a blade portion of a surgical cannulated blade instrument to create an opening in the cornea, injecting injectable into an anterior chamber of the eye through the opening by a lumen of the surgical cannulated blade, and stabilizing the eye by engaging an increasing diameter portion of the surgical cannulated blade with the opening.

A donor corneal tissue cutting blade provided with integrally formed asymmetrical markers for facilitation identification of the anterior and posterior sections or portions of the donor corneal tissue is disclosed. The blade is a cylindrical body having, in one embodiment, a U-shaped extension which cooperates with the body to define a keyway. Protrusions may be formed on the body and/or extension to provide further markers.

A medical knife has a flat projection shape of a cutting part formed in an approximate rhomboid shape including a front end part, a widest part with the largest width, and a side surface part formed between the front end part and the widest part. A front side bevel constituting an edge on the front side and a back side bevel constituting an edge on the back side are individually formed, having as a boundary a virtual surface including an edge formed along the periphery of the cutting part. A ratio of the angle β between the virtual surface and the back side bevel to the angle α between the virtual surface and the front side bevel at the front end part is greater than the ratio of the angle θ between the virtual surface and the back side bevel to the angle α at the side surface part.

A device for applying a marking to the human eye, in particular to the cornea of the eye, comprises a marking head comprising a marking element and a holding device carrying the marking head or an intermediate adapter. The marking head or the intermediate adapter has a bearing area which is rotatably mounted in a bearing ring of the holding device which surrounds the bearing area in a predeterminable or variable angular position.