Device comprising polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicator monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10
and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

A wound dressing and a monitor device is disclosed, the wound dressing comprising a top layer; a first adhesive layer with a proximal surface configured for attachment of the wound dressing to the skin surface of a user; an absorbent core layer; an electrode assembly comprising a plurality of electrodes arranged on a distal side of the absorbent core layer; and a monitor interface configured for connecting the wound dressing to a monitor device, the monitor interface comprising a plurality of terminals configured to form electrical connections with respective terminals of the monitor device, wherein the wound dressing comprises a flexible element, the flexible element being bendable and/or twistable between a first flexible element end and a second flexible element end, and wherein the monitor interface comprises a coupling part positioned at the first flexible element end.

A wound therapy system includes a therapy unit, a wound dressing and an optional controller. The therapy unit is configured to deliver instillation fluid to a wound site. The wound dressing is formed from a plurality of discrete, individual blocks that are selectively separable from one another along a plurality of separation-lines, allowing the wound dressing to be customized to the shape and size of the wound site. By calculating the remaining blocks that define the wound dressing following customization, the volume of the wound dressing may be determined. The controller may be configured to deliver fluid to the wound site based on this calculated volume. The controller may also optionally be used to gauge the healing of the wound site over time by monitoring the changes in volume of customized wound dressings as wound dressings are replaced during the course of treatment of the wound site.

A lower extremity wound system can include a lower extremity wound treatment monitoring device and an external user interface. The monitoring device can be associated with a primary wound dressing. In general, the sensors would not be placed in direct contact with the wound, and may also include within a base unit and placed on a posterior calf of the patient. The base unit can include multiple sensors, a controller, and a communication module. The controller can receive and process information from the sensors, and algorithmically determine whether to communicate information relating to the information from the sensors via the communication module to an external recipient. The external wound care information system can receive the information from the sensors, and if appropriate, can prompt a patient to alter their behavior so they are in compliance with their wound treatment plan, or inform a patient-care provider of a status change.

Disclosed are apparatuses comprising at least one electrode element having a skin-facing surface; a skin contact layer comprising an adhesive composite, and an adhesive tape or bandage. Disclosed are methods comprising positioning one or more electrode assemblies on a target site of a subject, the one or more electrode assemblies comprising at least one electrode element having a skin-facing surface; a skin contact layer comprising a conductive adhesive composite, and an adhesive tape or bandage, wherein the at least one electrode element is electrically coupled to the skin contact layer. In some aspects, the methods further comprise removing at least one of the one or more electrode assemblies from the target site of the subject after a period of time. In some aspects, after removal of the one or more electrode assemblies, the target site is evaluated for an adverse event.

The present invention provides a sensing system, a smart wearing arrangement and a method of fabricating a sensing system. In accordance with illustrative embodiments, the sensing system comprises: a flexible substrate, at least one sensor device, a chip device, and at least one electrical line, the at least one electrical line electrically connecting the chip device and the at least one sensor device. Herein, the at least one sensor device, the chip device, and the at least one electrical line are integrated into the flexible substrate.

Devices and methods for encapsulating a portion of a wound dressing with biocompatible coating are disclosed. In some embodiments, a method includes coating a first side of a flexible wound contact layer of the wound dressing with a hydrophobic coating. The first side of the wound contact layer can support a plurality of electronic components. The method can further include coating a second side of the wound contact layer opposite the first side with the hydrophobic coating. The wound contact layer can be formed at least partially from hydrophilic material.

A wound dressing, a method of manufacturing a wound dressing, and a method of treating a patient are disclosed. The wound dressing may include an absorbent layer for absorbing wound exudate; and an obscuring element for at least partially obscuring a view of wound exudate absorbed by the absorbent layer in use.

Devices and methods for encapsulating a portion of a wound dressing with biocompatible coating are disclosed. In some embodiments, a method includes coating a first side of a flexible wound contact layer of the wound dressing with a hydrophobic coating. The first side of the wound contact layer can support a plurality of electronic components. The method can further include coating a second side of the wound contact layer opposite the first side with the hydrophobic coating. The wound contact layer can be formed at least partially from hydrophilic material.

Provided herein are methods for treating nail infections, in particular fungal nail infections, comprising applying a drug delivery system comprising a desiccant such as silica gel to an external surface of the infected nail.