The present invention relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.

The present invention generally relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.

The present invention generally relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.

Implementations of a medical pad having a perimeter side, a first surface, a second surface, and a plurality of openings. In some implementations, a method of using the medical pad includes positioning the medical pad on an area susceptible to the development of a bedsore or similar wound, such as a bony prominence or pressure point, to prevent the development of a bedsore or similar wound, and another method includes positioning the medical pad on a bedsore or similar wound to help the treatment and healing of the bedsore or similar wound.

A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein the drug and having a first delivery profile of the drug; a second polymeric adhesive matrix, in contact with said first polymeric adhesive matrix, having dispersed therein the drug and having a second delivery profile of the drug, wherein said second delivery profile is different from said first delivery profile; and a release liner in contact with the second polymeric adhesive matrix.

The first polymeric adhesive matrix can release the drug more quickly or more slowly than the second polymeric adhesive matrix. Through the selection of the two matrices, the delivery profile of the drug through the skin can be selectively modified and controlled.

A pressure bandage including an elastic sheet having a first coefficient of elasticity and an adhesive side. The pressure bandage may also include a resilient pad having a second coefficient of elasticity and affixed to the adhesive side of the elastic sheet. The elastic sheet has a first predetermined shape that is configured to be applied to a corresponding anatomical location on the body of a patient. The first coefficient of elasticity and the second coefficient of elasticity are related such that, when the elastic sheet is stretched and adhered to the body of the patient, the resilient pad applies a predetermined amount of pressure to the body of the patient.

A method of forming a fibrin hydrogel composition is described. The method comprises forming an aqueous solution comprising fibrinogen, fibrin-forming enzyme, and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further comprises reducing the salt concentration below the threshold concentration to form a fibrin hydrogel. In some embodiments, the aqueous solution further comprises a plasticizer. A fibrin composition is also described comprising a fibrin hydrogel having a fibrin concentration ranging from 0.1 to 10 wt-%; and a fibrin hydrogel forming salt. The fibrin hydrogel forming salt has a concentration less than a threshold concentration to form the fibrin hydrogel. The fibrin hydrogel or dehydrated fibrin hydrogel can be in various physical forms such a sheet, foam, or plurality of pieces. Also described are methods of forming a fibrin article, wound dressings and a method of treatment of a wound.

The present invention relates to a haemostatic material comprising a carrier layer and a material for wound contact comprising at least one haemostat in particulate, granular, powder, flake or short fibrous form. Such a haemostatic material is useful, for example, in reducing or stopping bleeding of a physiological target site in a person or animal, and can also be used to stem bleeding during medical procedures.

A transdermal drug-containing dosage unit comprises: a backing layer substantially impervious to the drug to be delivered transdermally; a first polymeric adhesive matrix, in contact with the backing layer, having dispersed therein the drug and having a first delivery profile of the drug; a second polymeric adhesive matrix, in contact with said first polymeric adhesive matrix, having dispersed therein the drug and having a second delivery profile of the drug, wherein said second delivery profile is different from said first delivery profile; and a release liner in contact with the second polymeric adhesive matrix.

The first polymeric adhesive matrix can release the drug more quickly or more slowly than the second polymeric adhesive matrix. Through the selection of the two matrices, the delivery profile of the drug through the skin can be selectively modified and controlled.

An apparatus and process for applying a coating material onto a substrate as a non-uniform layer of coating material, the method including providing a distribution manifold having a cavity and a plurality of dispensing outlets in fluid communication with the cavity, creating relative motion between a substrate and the dispensing outlets in a first direction, and dispensing coating material from the dispensing outlets while simultaneously translating the plurality of dispensing outlets in a second direction non-parallel to the first direction. Using the process, coated articles having a useful non-uniform coating or coatings can be prepared, in particular self-adhesive vapor permeable air and moisture barrier membranes for use as architectural structure wraps.