The present disclosure relates to a dermal drug delivery platform comprising: a primary wound dressing comprising three-dimensional polymer protuberances that extend upward from the dressing surface to engage the wound. The protuberances comprise at least one biocompatible and/or biodegradable polymer and medicinal nanoparticles. In one embodiment, the medicinal nanoparticles may be metallic and provide surface-area-enhanced galvanic action to drive medicinal ions into the wound bed. Various methods of making the disclosed dermal drug delivery platform, as well as three-dimensional methods of treating a wound using the platform are also disclosed.

Disclosed is a wound dressing material comprising a substrate, about 2.5% to about 8% by weight of a bicarbonate, and a film-forming agent, the film-forming agent serving as a binder for said bicarbonate to said substrate, the film-forming agent and the bicarbonate being present in a ratio of between 1:2 and 2:1 with respect to one another. Also disclosed are a method for preparing a wound dressing material and a method for treating a wound.

A method for fabricating a bandage comprises the following steps: preparing multiple complex yarns each comprising chitosan fibers and rayon fibers; (b) weaving solely the multiple complex yarns to form a preformed bandage; (c) immersing the preformed bandage in an acid alcohol, and then washing the preformed bandage by alcohol to obtain an alcohol-washed bandage; and, (d) heating the alcohol-washed bandage to obtain the bandage. The bandage related to the method is comprised of complex yarns, wherein each of the complex yarns is composed of chitosan fibers and rayon fibers. By means of immersing the preformed bandage into an acid alcohol, the bandage thus obtained has enhanced tensile strength, decreased dissolution rate and reduced hemolytic dose.

A manifold member for use in applying reduced pressure to a tissue site on a patient looks or feels like medical cotton gauze but has a plurality of plurality of interlocking synthetic fibers and a plurality of asperities that provide enhanced performance. Other manifold members, systems, and methods are disclosed.

A manifold member for use in applying reduced pressure to a tissue site on a patient looks or feels like medical cotton gauze but has a plurality of plurality of interlocking synthetic fibers and a plurality of asperities that provide enhanced performance. Other manifold members, systems, and methods are disclosed.

Disclosed are solid dressings for treating wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of a fibrinogen component and a fibrinogen activator, wherein the haemostatic layer(s) is cast or formed from a single aqueous solution containing the fibrinogen component and the fibrinogen activator. Also disclosed are methods for treating wounded tissue using these dressings and frozen compositions useful for preparing the haemostatic layer(s) of these dressings.

A decorative splint material includes a moisture-curable material adapted to be wetted and molded into a splint configuration that conforms to an anatomical body part. The material hardens via a curing process to retain the splint configuration. The splint material includes a plurality of decorative elements integrated with the splint material. The decorative elements are provided on a substrate which is overlaid onto the moisture-curable material, and the substrate is overlaid with a flexible sheet having a plurality of openings which align with the decorative elements. The decorative elements are retained by the sheet of splint material when the sheet is wetted, molded into a splint configuration, and hardened.

The present invention relates to free-form structures made by additive manufacturing, and methods for the manufacture thereof. The rigid free-form structures comprise a lattice structure which is impregnated by a polymeric or other material. The rigid free-form structures may be used in wound treatment, e.g., as a facial mask.

A decorative splint material includes a moisture-curable material adapted to be wetted and molded into a splint configuration that conforms to an anatomical body part. The material hardens via a curing process to retain the splint configuration. The splint material includes a plurality of decorative elements integrated with the splint material. The decorative elements are provided on a substrate which is overlaid onto the moisture-curable material, and the substrate is overlaid with a flexible sheet having a plurality of openings which align with the decorative elements. The decorative elements are retained by the sheet of splint material when the sheet is wetted, molded into a splint configuration, and hardened.

An article. The article includes a nonwoven matrix; and bioactive glass particles enmeshed in the nonwoven matrix; wherein the article is a conformable wound dressing. A method of making the article includes flowing molten polymer through a plurality of orifices to form filaments; attenuating the filaments into fibers; directing a stream of bioactive glass particles amidst the filaments or fibers; and collecting a nonwoven matrix and bioactive glass particles enmeshed in the nonwoven matrix.