A wound debridement system includes a wound dressing having an active layer and a wound interface layer. The active layer is formed from one or more drive elements arranged about a film layer, by which the drive elements are attached to the wound interface layer. Activation of the drive elements is configured to cause the movement of the wound interface layer relative to a tissue site to which the wound dressing is applied. The drive elements may include one or more drive members formed of a material having a shape memory effect configured to transition the drive members between expanded and collapsed configurations and/or one or more motors configured to translate or oscillate the active layer. The wound interface layer may be formed having an abrasive wound-facing surface, such that the movement of the wound interface layer causes a mechanical disruption and debridement of debris at the tissue site.

A would dressing includes an absorbent core including a top carrier layer and a bottom carrier layer, a superabsorbent substance dispersed between the top carrier layer and the bottom carrier layer and the bottom carrier layer, and a shell formed by a facing layer and a backing layer. The absorbent core is located in the shell between the facing layer and the backing layer. The facing layer and the backing layer each can include a supporting structure. The supporting structure of the facing layer and the supporting structure of the backing layer each can include an inner surface facing towards the absorbent core and an outer surface facing away from the absorbent core. The outer surface of the supporting structure of the facing layer and/or the outer surface of the supporting structure of the backing layer can be laminated with a foam layer.

Fibres suitable for use in the production of wound dressings comprise carboxymethyl cellulose and alginate in a total amount of at least 90% by weight of the fibre, the carboxymethyl cellulose and alginate are homogeneously distributed throughout the fibre and are present in amounts such that: (a) the amount of carboxymethyl cellulose present in the fibre is at least 50% by weight of the total weight of the carboxymethyl cellulose and alginate; (b) the alginate has a Guluronate-content of 50-90% by weight, and (c) the value of z given by the expression (1): z=(2x/40)/(2x/40)+(y/23) where x and y are the percentages by weight of calcium and sodium respectively in the fibres is at least 80. The fibres may be produced by spinning a solution comprising dissolved CMC and alginate in appropriate proportions into a coagulation bath containing calcium ions.

Antimicrobial dressings for prevention and mitigation of biofilm and bacterial infection by an applied electric current are provided. Methods of making the dressings and methods of applying an electric current to promote the wound healing process are also disclosed.

The compressive bandage includes an elastic cap to fit over the patient's head wound and head. The cap is impervious to fluid and has a fluid pervious inboard sleeve pocket. An absorbent pad placed in the sleeve since the sleeve and the cap expands. The loaded bandage is placed on the head wound. The pocket patch is a micro fiber, polyester fabric, preferably NIKE DRY FIT material. The head wound is stanched by placing the over the head wound. After the first use and after removal from the wounded head, the first pad is withdrawn from the pocket, a second pad in inserted and the compressive bandage is again placed on the head wound. After the first use or the second use, the bandage can be washed and sterilized.

Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be positioned adjacent a distal opening of the tissue space, and expanded to seal the distal opening. A hemostatic agent may be applied from the catheter to the internal surface of the tissue space to inhibit bleeding of the tissue space. The hemostatic agent may be applied without occluding the proximal opening, the distal opening, and a path extending therebetween with the hemostatic agent.

The present disclosure provides sulfhydryl-modified polymer foams, which may be used for wound dressing materials. For example, the modified materials can include free sulfhydryl group, which can serve as a linker to attach biologically active molecules. For example, sulfhydryl groups can be used to conjugate biologically active polypeptides and/or metals to foam polymers. Methods for using sulfhydryl-modified polymers, such as for wound dressings, are also provided.

Disclosed are compositions that comprise an organic electrochemical mediator and a gasotransmitter salt which converts into a gasotransmitter via electron transfer. Also disclosed are bandages and wound dressings comprising the subject gasotransmitters, and methods of making a gasotransmitters, comprising exposing the compositions to a voltage sufficient to reduce the water soluble organic mediator. Further disclosed are methods of treating a variety of trauma and disease states by applying a therapeutically effective amount of at least one gasotransmitter thereto, and methods of generating an effective dose of the gasotransmitter generated from electrolytic reaction involving the gasotransmitter-generating compositions.

A wound debridement system includes a wound dressing having an active layer and a wound interface layer. The active layer is formed from one or more drive elements arranged about a film layer, by which the drive elements are attached to the wound interface layer. Activation of the drive elements is configured to cause the movement of the wound interface layer relative to a tissue site to which the wound dressing is applied. The drive elements may include one or more drive members formed of a material having a shape memory effect configured to transition the drive members between expanded and collapsed configurations and/or one or more motors configured to translate or oscillate the active layer. The wound interface layer may be formed having an abrasive wound-facing surface, such that the movement of the wound interface layer causes a mechanical disruption and debridement of debris at the tissue site.

The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to bioresorbable hemostatic pads or patches releasably supported on non-resorbable scaffolds for ease of delivery in the field. A sealant and/or hemostat delivery device comprises a resorbable hemostatic pad having a wound facing side and an opposite back side, with a hemostatic and/or wound sealing agent disposed on the wound facing side; a non-resorbable scaffold having an attachment zone on said scaffold; wherein said hemostatic pad is releasably attached with the back side to the attachment zone. The bond between the scaffold and the resorbable hemostatic pad or wound dressing is either (i) severed prior to removal of the scaffold or (ii) is weakened due to the adhesive bonding them together being moisture-deactivated, or (iii) is released by mechanical disentanglement.