Patent classifications
C07D251/46
Polyether group-containing compound
A polyether group-containing compound of the formula (I). In each of the compound of the formula (I), one or two R are represented by (Rf-X.sup.f1-PE-X.sup.f2).sub.?X.sup.1, and one or two R are represented by R.sup.Si. The symbols are as defined in the description. ##STR00001##
Polyether group-containing compound
A polyether group-containing compound of the formula (I). In each of the compound of the formula (I), one or two R are represented by (Rf-X.sup.f1-PE-X.sup.f2).sub.?X.sup.1, and one or two R are represented by R.sup.Si. The symbols are as defined in the description. ##STR00001##
CFTR regulators and methods of use thereof
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.
CFTR regulators and methods of use thereof
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.
NITROGEN-CONTAINING HETEROCYCLIC KETONES, PREPARATION METHODS AND MEDICINAL USES THEREOF
Provided herein is novel N-heterocyclic ketones that are useful for treatment of hypertrophic cardiomyopathy (HCM) and other heart diseases. The preparation method thereof, pharmaceutical compositions comprising the compound.
CFTR REGULATORS AND METHODS OF USE THEREOF
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.
CFTR REGULATORS AND METHODS OF USE THEREOF
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.
TRIAZINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AND NEURODEGENERATIVE DISORDERS
The present invention relates to compounds of Formula (I) to their pharmaceutical composition and their use as a medicament, in particular for the treatment and/or prevention of a tumour, viral infection, bacterial infection or neurodegenerative disease.
##STR00001##
TRIAZINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AND NEURODEGENERATIVE DISORDERS
The present invention relates to compounds of Formula (I) to their pharmaceutical composition and their use as a medicament, in particular for the treatment and/or prevention of a tumour, viral infection, bacterial infection or neurodegenerative disease.
##STR00001##
Methods and compositions for treating anxiety
Methods of treating a TRPC5 mediated disorder in a subject by administering an effective amount of a TRPC5 antagonist, such as a compound disclosed herein, are described.