Patent classifications
C07D251/52
IDH1 INHIBITORS FOR THE TREATMENT OF HAEMATOLOGICAL MALGNANCIES AND SOLID TUMORS
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
Methods of treatment of malignancies
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
Methods of treatment of malignancies
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
Polyether group-containing compound
A polyether group-containing compound of the formula (I). In each of the compound of the formula (I), one or two R are represented by (Rf-X.sup.f1-PE-X.sup.f2).sub.?X.sup.1, and one or two R are represented by R.sup.Si. The symbols are as defined in the description. ##STR00001##
Polyether group-containing compound
A polyether group-containing compound of the formula (I). In each of the compound of the formula (I), one or two R are represented by (Rf-X.sup.f1-PE-X.sup.f2).sub.?X.sup.1, and one or two R are represented by R.sup.Si. The symbols are as defined in the description. ##STR00001##
CFTR regulators and methods of use thereof
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.
CFTR regulators and methods of use thereof
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.
Methods of treatment of malignancies
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
Methods of treatment of malignancies
Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation or IDH2 mutation.
CFTR REGULATORS AND METHODS OF USE THEREOF
Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.