C07D251/66

PIKfyve inhibitors

The present application provides, inter alia, a compound of Formula (I): ##STR00001##
or a pharmaceutically acceptable salt thereof, wherein Y, Ar, X.sup.1, X.sup.2, X.sup.3, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as described herein. Methods of making these compounds and methods of using these compound for treating diseases such as cancer are also provided.

PIKfyve inhibitors

The present application provides, inter alia, a compound of Formula (I): ##STR00001##
or a pharmaceutically acceptable salt thereof, wherein Y, Ar, X.sup.1, X.sup.2, X.sup.3, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as described herein. Methods of making these compounds and methods of using these compound for treating diseases such as cancer are also provided.

PIKfyve Inhibitors

The present application provides, inter alia, a compound of Formula (I):

##STR00001## or a pharmaceutically acceptable salt thereof, wherein Y, Ar, X.sup.1, X.sup.2, X.sup.3, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as described herein. Methods of making these compounds and methods of using these compound for treating diseases such as cancer are also provided.

PIKfyve Inhibitors

The present application provides, inter alia, a compound of Formula (I):

##STR00001## or a pharmaceutically acceptable salt thereof, wherein Y, Ar, X.sup.1, X.sup.2, X.sup.3, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 are as described herein. Methods of making these compounds and methods of using these compound for treating diseases such as cancer are also provided.

Chemical foaming agents containing tosyl groups

Chemical foaming agents having p-toluenesulfonyl groups. Processes for preparing foamed polyolefin compositions using chemical foaming agents having p-toluenesulfonyl groups. Articles of manufacture containing formed polyolefins prepared using chemical foaming agents having p-toluenesulfonyl groups.

Chemical foaming agents containing tosyl groups

Chemical foaming agents having p-toluenesulfonyl groups. Processes for preparing foamed polyolefin compositions using chemical foaming agents having p-toluenesulfonyl groups. Articles of manufacture containing formed polyolefins prepared using chemical foaming agents having p-toluenesulfonyl groups.