An applicator has a stem, one or more tips, and one or more chambers which may hold therapeutic or medicinal fluids. The applicator may be separated into two sections so the tips can be used independently. The fluids held in the chambers may be separated with one or more frangible walls which can be broken to release or mix the fluids. The tips are used as applicators for the therapeutic or medicinal effects produced by the fluids or the medicines contained in the cavity.

An applicator has a stem, one or more tips, and one or more chambers which may hold therapeutic or medicinal fluids. The applicator may be separated into two sections so the tips can be used independently. The fluids held in the chambers may be separated with one or more frangible walls which can be broken to release or mix the fluids. The tips are used as applicators for the therapeutic or medicinal effects produced by the fluids or the medicines contained in the cavity.

The invention is generally a nasal pharyngeal and oral swab that may be mass-produced via three-dimensional (3D) printing. To achieve the right materials for 3D printing the swabs, exemplary embodiments employ a set of materials that result in a rigid structure that has bendable properties (at least in the neck or stem region of the swab), but more rigid and bridle properties at a breakpoint of the swab. In exemplary embodiments, this may be achieved by constructing the device of a first photosensitive material that is generally soft and bendable when cured, and a second photosensitive material that is generally rigid and brittle when cured, wherein the soft bendable material comprises of about 70% to 90% of the photosensitive composition used to 3D print the swab, and the rigid and brittle material comprises of about 30% to 10% of the photosensitive composition used to 3D print the swab.

Article for sampling comprising inner layer, one or more outer layers, and optional scouring layer on a portion of the one or more outer layers.

Article for sampling comprising inner layer, one or more outer layers, and optional scouring layer on a portion of the one or more outer layers.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

A method and apparatus for treating ocular disorders such as blepharitis, meibomitis, and dry eye syndrome. The method includes using an electromechanical device to move a swab relative to the eye to create cyclical movement that impacts debris present at the eyelid margin and effectively removes the debris from the eye to encourage healing and prevent further digression of the health of the eye. The apparatus is an electromechanical device that includes a mechanical drive unit operatively connected to a swab to create a precise relative movement of the swab to the eye to remove debris present therein.

A method and apparatus for treating ocular disorders such as blepharitis, meibomitis, and dry eye syndrome. The method includes using an electromechanical device to move a swab relative to the eye to create cyclical movement that impacts debris present at the eyelid margin and effectively removes the debris from the eye to encourage healing and prevent further digression of the health of the eye. The apparatus is an electromechanical device that includes a mechanical drive unit operatively connected to a swab to create a precise relative movement of the swab to the eye to remove debris present therein.

An apparatus for testing for streptococcal pharyngitis includes a tube having an open first end and a second end, and an opening on a side thereof, a dipstick inserted into the tube through the side opening, and an insert with a hole that can receive the dipstick and sized to nest the dipstick into the side opening of the tube. A swab at the end of the dipstick inside the tube receives microbes in a breath exhaled by a patient holding the first end of the tube to the patient's mouth. After being exhaled upon by the patient, the dipstick is removed for testing for the presence of microbes that cause streptococcal pharyngitis.