Patent classifications
C07D311/36
ACYLATED ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF AUTOIMMUNE DISORDERS
Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.
ACYLATED ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF AUTOIMMUNE DISORDERS
Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.
Intermediates useful in the synthesis of compounds as modulators of protein kinases
The present invention provides compounds of formula (10), formula (12), formula (14) and formula (15) ##STR00001## wherein R, R.sup.1, R.sup.2, Cy.sup.1 and X are as described herein.
Intermediates useful in the synthesis of compounds as modulators of protein kinases
The present invention provides compounds of formula (10), formula (12), formula (14) and formula (15) ##STR00001## wherein R, R.sup.1, R.sup.2, Cy.sup.1 and X are as described herein.
Acylated active agents and methods of their use for the treatment of autoimmune disorders
Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.
Kinase modulators
The present invention provides PI3K protein kinase modulators of Formula (I) ##STR00001##
wherein R, n, R.sup.1, R.sup.2, L.sup.1, Cy.sup.1 and Cy.sup.2 are as defined herein, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.
Kinase modulators
The present invention provides PI3K protein kinase modulators of Formula (I) ##STR00001##
wherein R, n, R.sup.1, R.sup.2, L.sup.1, Cy.sup.1 and Cy.sup.2 are as defined herein, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.
NOVEL KINASE MODULATORS
The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.
NOVEL KINASE MODULATORS
The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.
ACYLATED ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF AUTOIMMUNE DISORDERS
Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.