Patent classifications
C07F9/3229
SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
Sulfur derivatives as chemokine receptor modulators
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE 1 (DGAT-1) AND USES THEREOF
This invention pertains to the use of fused bicycle heterocyclic adducts of thiohydroxy pyridines or pyrimidines as diacylglycerol O-acyltransferase 1 (DGAT-1) inhibitors to treat hyperlipidiemias and various diseases and disorders associated therewith. Other conditions also be ameliorated or avoided, such as high postprandial triglycerides or diet-related hypertriglyceridemia, cardiovascular risk associated with excessive triglycerides, and insulin resistance/glucose intolerance in overweight patients, those with diabetes or other glucose metabolic disorders such as Syndrome X and/or polycystic ovary disease.
Multifunctional acylphosphine oxide photoinitiators
The present invention relates to a series of novel multifunctional mono- and bis-acylphosphine oxides, which are useful as photoinitiators, and to photocurable compositions comprising said photoinitiators.
PHOPHORUS CONTAINING MONOMER OR OLIGOMER, POLYESTER RESIN COMPRISING SAME, AND THERMOPLASTIC RESIN COMPOSITION
A phosphorus (P) containing monomer or oligomer represented by Chemical Formula 1, a polyester resin including a constitutional unit derived from the phosphorus containing monomer or oligomer, a thermoplastic resin composition including the polyester resin, and a molded article including the polyester resin are provided. The constitutional unit derived from the phosphorus containing monomer or oligomer provides excellent flame retardancy and a high degree of polymerization of the polyester resin.
##STR00001##
Water-soluble complexing agents and corresponding lanthanide complexes
The invention relates to complexing agents of formula (I): ##STR00001##
in which A, chrom1, chrom2 and chrom3 are as defined in the description. The invention also relates to the lanthanide complexes obtained from these complexing agents.
Class of HDAC Inhibitors Expands the Renal Progenitor Cells Population and Improves the Rate of Recovery from Acute Kidney Injury
Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.
Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury
Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.
Sulfur derivatives as chemokine receptor modulators
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
SULFUR DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.