C07F9/4075

Biodegradable compound, lipid particle, composition containing lipid particle, and kit

The compound according to the present embodiment is represented by the following formula (1):
Q-L-CHR.sub.2(1)
(wherein, Q is a non-cationic aliphatic group that does not contain nitrogen but contains oxy; L is a single bond or an aliphatic group containing no nitrogen; Rs are C.sub.12-C.sub.24 aliphatic group, the same or different; and at least one R contains, in the main chain or side chain thereof, a linking group L.sup.R selected from the group consisting of C(O)O, OC(O), OC(O)O, SC(O), C(O)S, C(O)NH, and NHC(O)).

Process for producing phosphinates
20200079804 · 2020-03-12 ·

The present invention relates primarily to a process for producing particular phosphinates (phosphonous acid monoesters) and use thereof for producing biologically active substances which may be used in the pharmaceutical or agrochemical sector, preferably for producing phosphorus-containing amino acids.

Supported molybdenum peroxo complexes for transforming organo phosphate neurotoxins to a value-added, commodity phosphorus chemical
10533026 · 2020-01-14 · ·

The invention relates to degradation of organophosphate neurotoxins with molybdenum complexes. In particular, the degradation of phosphate ester neurotoxins can be performed with molybdenum peroxo complexes resulting in recoverable phosphorus-containing compounds.

Hardener and cure accelerant with flame retardancy effect for curing epoxy resins (II)

The present invention relates to novel hardeners for curing epoxy resins and to cure accelerants for the accelerated curing of epoxy resins comprising, in each case, at least one compound from the group of esters of phosphorus-containing acids according to Formula (I), wherein there applies to Formula (I): ##STR00001##
wherein there applies to the radicals R.sup.1, R.sup.2, R.sup.3, R.sup.6, X and indices m, n, p, simultaneously or independently of one another: R.sup.1, R.sup.2=simultaneously or independently of one another, hydrogen or alkyl, R.sup.3=alkyl, aryl, O-alkyl, O-aryl, O-alkylaryl or O-arylalkyl, R.sup.6=hydrogen, alkyl or NHC(O)NR.sup.1R.sup.2, X=oxygen or sulphur, m=1, 2 or 3, n=0, 1 or 2, wherein there applies: m+n=3 p=0, 1 or 2.

Prodrugs of prostate specific membrane antigen (PSMA) inhibitor

Methods and compounds are disclosed for treating a disease or condition by inhibiting PSMA (Prostate Specific Membrane Antigen) using prodrugs of 2-PMPA.

Process for producing phosphinates
10501485 · 2019-12-10 · ·

The present invention relates primarily to a process for producing particular phosphinates (phosphonous acid monoesters) and use thereof for producing biologically active substances which may be used in the pharmaceutical or agrochemical sector, preferably for producing phosphorus-containing amino acids.

PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS

The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.

Aminobisphosphonate antiwear additives

The present invention relates to novel aminobisphosphonate compounds useful as antiwear and/or friction modifier additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, and methods for making and using the same.

BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION CONTAINING LIPID PARTICLE, AND KIT

The compound according to the present embodiment is represented by the following formula (1):


Q-LCHR.sub.2 (1)

(wherein, Q is a non-cationic aliphatic group that does not contain nitrogen but contains oxy; L is a single bond or an aliphatic group containing no nitrogen; Rs are C.sub.12-C.sub.24 aliphatic group, the same or different; and at least one R contains, in the main chain or side chain thereof, a linking group L.sup.R selected from the group consisting of C(O)O, OC(O), OC(O)O, SC(O), C(O)S, C(O)NH, and NHC(O)).

Processes and intermediates for preparing anti-HIV agents

The invention provides synthetic processes and synthetic intermediates that can be used to prepare compounds having useful anti-HIV properties.