The disclosure describes an annuloplasty device that includes a wire configured to extend around at least part of an annulus of a cardiac or vascular valve, such as at least partially around a circumference of the annulus, and a plurality of anchors. The anchors of the plurality of anchors are configured to engage the wire and anchor the wire to the annulus. The wire is configured to urge at least some anchors of the plurality of anchors toward each other in a radially inward direction to decrease a distance between valve leaflets that extend from the annulus.

Implantable in vivo sensors used to monitor physical, chemical or electrical parameters within a body. The in vivo sensors are integral with an implantable medical device and are responsive to externally or internally applied energy. Upon application of energy, the sensors undergo a phase change in at least part of the material of the device which is then detected external to the body by conventional techniques such as radiography, ultrasound imaging, magnetic resonance imaging, radio frequency imaging or the like. The in vivo sensors of the present invention may be employed to provide volumetric measurements, flow rate measurements, pressure measurements, electrical measurements, biochemical measurements, temperature, measurements, or measure the degree and type of deposits within the lumen of an endoluminal implant, such as a stent or other type of endoluminal conduit. The in vivo sensors may also be used therapeutically to modulate mechanical and/or physical properties of the endoluminal implant in response to the sensed or monitored parameter.

A replacement heart valve comprising a memory shape element. The various embodiments use internal body heat to seat and retain the valve within a blood passage. The element can be provided in a variety of shapes and sizes, and is at least partially encased within an inert and pliant encasing material. The encasing material is one that is adapted to be contiguous with the structure of the valve nozzle or backflow-resistant leaf structure, and may be used in combination with existing stents or an incorporated stent, including ones having a structure similar to conventional stents.

An implant (fixture) device, systems, and methods for providing a fixture in, and/or around, and/or on, a substrate such a bone. The implant includes a hollow body composed of a shape-memory material. The hollow body includes a plurality of sections connected to each other and separated by an opening between the sections. The plurality of sections are configured to have a compact configuration and/or an expanded configuration and may change between the first configuration and the second configuration in response to an applied stimulus. The opening and the plurality of sections may be in the shape of a spiral.

A method of sequenced deployment of an endovascular device comprises delivering, into a body vessel, a Nitinol structural element comprising n deployable regions each having a local austenite finish temperature above body temperature. The local austenite finish temperature of at least one of the n deployable regions is different from the local austenite finish temperature of another of the n deployable regions. During and/or after delivery, the Nitinol structural element is heated above body temperature, and each of the n deployable regions is deployed when the local austenite finish temperature thereof is reached. Thus, a deployed configuration of an endovascular device is achieved in a sequenced deployment process.

An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.

A scleral prosthesis includes an elongated body having a first free end, a second free end opposite the first free end, a central portion extending between and coupling the ends, and a convex top surface extending lengthwise along at least part of the central portion. A maximum width of the body at each end is wider than a maximum width of the body along the central portion. The scleral prosthesis also includes an insert having a convex top surface extending lengthwise along at least part of the insert. The body includes multiple portions that form the first end and part of the central portion. The portions are separated lengthwise along part of a total length of the body by empty space, which tapers and then expands in width. The insert has a shape complementary to the empty space such that the insert tapers and then expands in width.

An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.

An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.

A scleral prosthesis includes an elongated body having a first free end, a second free end opposite the first free end, a central portion extending between and coupling the ends, and a convex top surface extending lengthwise along at least part of the central portion. A maximum width of the body at each end is wider than a maximum width of the body along the central portion. The scleral prosthesis also includes an insert having a convex top surface extending lengthwise along at least part of the insert. The body includes multiple portions that form the first end and part of the central portion. The portions are separated lengthwise along part of a total length of the body by empty space, which tapers and then expands in width. The insert has a shape complementary to the empty space such that the insert tapers and then expands in width.