Described herein are implant loading and delivery systems for treating heart failure. An implant loading system may include a funnel having a flared first end and a second end, such that the flared first end is configured for receiving and collapsing the expandable implant, and a sleeve removably coupled to the second end of the funnel and configured to transfer the expandable implant to a guide catheter. The expandable device may have a foot for contacting a first interior wall portion of a heart, a support frame including a plurality of radially expandable struts, and a membrane coupled to the support frame. The expandable device may be coupled to a delivery catheter. An expansion member coupled to a distal end of the delivery catheter may apply pressure to the support frame of the expandable device to move the expandable device from a collapsed configuration to an expanded deployed configuration.

A radiopaque marker bead can be attached to an endoprosthesis by pressing an end of bead into a through hole formed into the endoprosthesis and allowing the opposite end of the bead to pass through the hole and protrude out of the other end of the hole. Both ends of the bead can then be pressed and flattened so as to frictionally engage both ends of the hole. A support tool having a curved outer surface can be inserted into the endoprosthesis to support the endoprosthesis luminal surface while the bead is being pushed into the hole. The support tool has a depression which allows the opposite end of the bead to protrude out of the hole.

A facet joint replacement system includes an inferior implant with an inferior articular surface, a superior implant with a superior articular surface and may include a crosslink extending across a vertebral sagittal plane. The inferior implant may comprise an inferior strut, and a polyaxially adjustable, lockable mechanism which may couple the inferior articular surface with a first end of the inferior strut, and couple the inferior articular surface with the crosslink. A second end of the inferior strut may be secured to a polyaxially adjustable, lockable fixation assembly securable in a vertebra. The superior implant may be secured to a polyaxially adjustable lockable fixation assembly securable in a vertebra. The positions of the inferior articular surface and the first end of the inferior strut are independently translatable along a medial-lateral axis of the vertebra prior to lockout by the lockable mechanism. The crosslink may be placed into the lockable mechanism from a posterior approach.

A spinal fusion device for implantation between spinal vertebrae includes an implant member having an opposed upper and lower surface, an outer sidewall having an aperture having internal threads, and an inner sidewall defining a central opening. A plate member is attached to the implant member such that the plate member is perpendicular relative to the implant member and includes a plurality of angled apertures for receiving anchoring fasteners and a central aperture for receiving a locking fastener. A locking member is attached to the cage member. The locking member includes a tubular shaft having internal threads that is inserted through the aperture of the outer sidewall of the implant member. A locking fastener is inserted through the central aperture of the plate member and into the locking member to thereby lock the spinal fusion device in position.

Embodiments herein are generally directed to vertebral implants and implant trials for use with vertebral implant assemblies. In some embodiments, these implants and implant trials may be used in conjunction with corpectomy procedures.

An expandable implant includes a body portion, a carriage portion, a deployment assembly, and an expandable portion. The deployment assembly and the expandable portion are attached to the carriage portion, and portions of the carriage portion are moveable out of and into the body portion. When the expandable implant is inserted into a disc space, the expandable portion is expandable to push the upper vertebral body and the lower vertebral body away from one another.

The present invention has multiple aspects relating to a bone-tendon-bone graft and components thereof. Embodiments of the present invention comprise an intermediate bone block that is used to adjustably secure soft tissue (e.g., tendon) in a patient. The present invention further relates to an assembled bone-tendon-bone graft suitable for implantation in humans comprising the intermediate bone block and a length of soft tissue. In a preferred embodiment, a bone-tendon-bone graft comprises a length of soft tissue (e.g., tendon) extending from a first assembled bone block to a second bone block and then doubles back to said first assembled bone block. Depending upon the embodiment, the second bone block fixedly or slideably attaches to the length of soft tissue and facilitates it doubling back to the first assembled bone block.

An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve. Other embodiments are also described.

Anchoring devices, anchoring systems for intervertebral implants, intervertebral implants, and instruments and methods for implanting implants are disclosed. In preferred configurations, these various objects share the feature of comprising or cooperating with an anchoring device having a body comprising at least one curved plate elongated along a longitudinal axis, designed to be inserted through a passage crossing at least a part of implant, in order to penetrate into at least one vertebral endplate and attach implant onto this vertebral endplate by means of at least one stop retaining the implant, characterized in that the body comprises at least one longitudinal rib on at least a part of at least one of its faces, said rib being designed to cooperate with a groove made in passage of implant. In some preferred configurations, anchoring device comprises withdrawal stops or latches, and/or means for withdrawing the anchor from an inserted position.

A placeholder for vertebrae or vertebral discs includes a tubular body, which along its jacket surface has a plurality of breakthroughs or openings for over-growth with adjacent tissue. The placeholder includes at least a second tubular body provided with a plurality of breakthroughs and openings at least partially inside the first tubular body. The first and second tubular bodies can have different cross-sectional shapes, can be are arranged inside one another by press fit or force fit or can be connected to each other via connecting pins and arranged side by side to one another in the first body.