C07F9/65746

Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Phenolic Antioxidants
20220145053 · 2022-05-12 ·

Polyolefin compositions comprising i) a polyolefin, ii) one or more phosphorus-containing benzofuranone compounds and iii) one or more hindered phenolic antioxidants are provided excellent protection against discoloration and enhanced thermal stability during melt processing as exhibited by improved retention of molecular weight and maintenance of polymer molecular architecture.

Electrolyte Solution for Lithium Secondary Battery and Lithium Secondary Battery Including the Same
20220140393 · 2022-05-05 ·

An electrolyte solution for a lithium secondary battery includes an organic solvent, a lithium salt, and a pentaerythritol diphosphite-based compound including at least one substituent selected from the group consisting of a silyl group, a sulfonyl group, a phosphoryl group and a phosphino group. A lithium secondary including the electrolyte solution is provided.

Bisphosphite ligands based on benzopinacol with an open outer unit

Bisphosphite ligands based on benzopinacol with an open outer unit, and the use thereof in hydroformylation.

PREPARATION OF ORGANOSILICON COMPOUNDS WITH ALDEHYDE FUNCTIONALITY

A catalyzed hydroformylation process of an alkenyl-functional organosilicon compound with carbon monoxide and hydrogen produces an aldehyde-functional organosilicon compound.

3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers

The invention relates to a composition comprising an organic material susceptible to oxidative, thermal or light-induced degradation and a compound of formula I-P, I-O or I-M. Further embodiments are a compound of formula I-P, I-O or I-M, a process for protection of the organic material by the compound, the use of the compound against degradation of the organic material, an additive composition comprising the compound, processes for manufacturing the compound and an intermediate involved therein. ##STR00001##

3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator

The present disclosure relates to 3′3′-cyclic dinucleotides having a carbocyclic nucleotide and derivatives that can modulate the activity of the STING adaptor protein.

INOSITOL-BASED IMMUNOTHERAPIES
20210361680 · 2021-11-25 ·

The present invention provides, inter alia, methods and compositions that are useful in the treatment of cancer.

Sting agonists

The present invention provides compounds of Formula I′: ##STR00001##
wherein custom character, W, X, Y, Z, Z.sub.1, Z.sub.2, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are effective at modulating the STING protein and thus can be used as medicaments for treating or preventing disorders affected by the agonism of STING.

Diphosphites having an open and a closed 2,4-methylated outer unit

Diphosphites having an open and a closed 2,4-methylated outer unit and use thereof in hydroformylation.

Stabilized Polyolefin Compositions Comprising Benzofuranones and Hindered Amine Light Stabilizers
20220259405 · 2022-08-18 ·

Polyolefin compositions comprising i) a polyolefin, ii) one or more phosphorus- containing benzofuranone compounds and iii) one or more hindered amine light stabilizers are provided excellent protection against discoloration and enhanced thermal stability during melt processing as exhibited by improved retention of molecular weight and maintenance of polymer molecular architecture.