C07H15/23

Substituted biphenyl or phenylheteroaryl-mannosides as antagonists of FimH

Disclosed herein are new O-biphenyl- and O-phenylheteroarylmannoside compounds and compositions and their application as pharmaceuticals for use in the treatment of human disease. Methods of inhibition of FimH activity in human subjects are also provided for the treatment of diseases such as urinary tract infection.

SUBSTITUTED BIPHENYL OR PHENYLHETEROARYL-MANNOSIDES AS ANTAGONISTS OF FIMH

Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in human subjects are also provided for the treatment diseases such as urinary tract infection.

SUBSTITUTED BIPHENYL OR PHENYLHETEROARYL-MANNOSIDES AS ANTAGONISTS OF FIMH

Disclosed herein are new C-mannoside compounds and compositions and their application as pharmaceuticals for the treatment of human disease. Methods of inhibition of FimH activity in human subjects are also provided for the treatment diseases such as urinary tract infection.