There are provided tissue repair laminates which promote cellular in-growth but also prevent or mitigate tissue adhesion. The laminates comprise a biodegradable polyurethane foam layer which facilitates cellular infiltration and a polyurethane barrier layer which is non-adhesive to tissue. The laminates resist shrinkage under in vivo conditions and possess desirable mechanical properties. The laminates find use in, for example, the repair of herniated tissue, particularly, but not limited to hernias in the abdominal wall.

There are provided tissue repair laminates which promote cellular in-growth but also prevent or mitigate tissue adhesion. The laminates comprise a biodegradable polyurethane foam layer which facilitates cellular infiltration and a polyurethane barrier layer which is non-adhesive to tissue. The laminates resist shrinkage under in vivo conditions and possess desirable mechanical properties. The laminates find use in, for example, the repair of herniated tissue, particularly, but not limited to hernias in the abdominal wall.

A polyurethane insulation foam composition is disclosed herein. The polyurethane insulation foam comprises: (i) an isocyanate compound; (ii) an isocyanate reactive compound; (iii) water; (iv) a heterocyclic amine compound; (v) a hydrophilic carboxylic acid compound; (vi) a halogenated olefin compound; and (vii) optionally, other additives.

A pour-in-place polyurethane insulation foam composition is disclosed herein. The polyurethane insulation foam comprises: (i) an isocyanate compound; (ii) an isocyanate reactive compound; (iii) water; (iv) a heterocyclic amine compound; (v) a hydrophilic carboxylic acid compound; (vi) a halogenated olefin compound; and (vii) optionally, other additives.

A polyurethane insulation foam composition is disclosed herein. The polyurethane insulation foam comprises: (i) an isocyanate compound; (ii) an isocyanate reactive compound; (iii) water; (iv) a tertiary amine compound; (v) a hydrophilic carboxylic acid compound; (vi) a halogenated olefin compound; and (vii) optionally, other additives.

There is provided a soft tissue implant pocket which reduces the incidence of capsular contracture. The pocket is manufactured from a biodegradable, biocompatible polyurethane foam. The polyurethane contains biodegradable polyols and the foam has a pore size configured for cellular infiltration. The soft tissue implant pocket find use in, for example, breast augmentation and reconstruction.

There is provided a soft tissue implant pocket which reduces the incidence of capsular contracture. The pocket is manufactured from a biodegradable, biocompatible polyurethane foam. The polyurethane contains biodegradable polyols and the foam has a pore size configured for cellular infiltration. The soft tissue implant pocket find use in, for example, breast augmentation and reconstruction.

The invention relates to a method for applying a material containing a meltable polymer comprising the step of applying a filament of the at least partially molten material from a discharge opening of a discharge element onto a substrate. The meltable polymer has the following properties: a melting point (DSC, differential scanning calorimetry; second heating with a heating rate of 5 C./min) in a range from 40 C. to 120 C.; a glass transition temperature (DMA, dynamic mechanical analysis in accordance with DIN EN ISO 6721-1:2011) in a range from 70 C. to 30 C.; a storage modulus G (parallel plate oscillation viscometer in accordance with ISO 6721-10:2015 at a frequency of 1/s) at 20 C. above the melting point of 1.Math.10.sup.4 Paa storage modulus G (parallel plate oscillation viscometer in accordance with ISO 6721-10:2015 at a frequency of 1/s) at 10 C. below the melting point with prior heating to a temperature of 20 C. above the melting point and subsequent cooling with a cooling rate of 1 C./min of 1.Math.10.sup.7 Pa; wherein the filament has an application temperature of 100 C. above the melting point of the meltable polymer for 5 minutes during the application process and wherein the meltable polymer further has the property that the storage modulus G (parallel plate oscillation viscometer in accordance with ISO 6721-10:2015 at a frequency of 1/s) of the meltable polymer at the highest application temperature reached during the application process is smaller by a factor of 10 than the storage modulus G (parallel plate oscillation viscometer in accordance with ISO 6721-10:2015 at a frequency of 1/s) at a temperature of 20 C. above the melting point of the meltable polymer.

There are provided tissue repair laminates which promote cellular in-growth but also prevent or mitigate tissue adhesion. The laminates comprise a biodegradable polyurethane foam layer which facilitates cellular infiltration and a polyurethane barrier layer which is non-adhesive to tissue. The laminates resist shrinkage under in vivo conditions and possess desirable mechanical properties. The laminates find use in, for example, the repair of herniated tissue, particularly, but not limited to hernias in the abdominal wall.

There are provided tissue repair laminates which promote cellular in-growth but also prevent or mitigate tissue adhesion. The laminates comprise a biodegradable polyurethane foam layer which facilitates cellular infiltration and a polyurethane barrier layer which is non-adhesive to tissue. The laminates resist shrinkage under in vivo conditions and possess desirable mechanical properties. The laminates find use in, for example, the repair of herniated tissue, particularly, but not limited to hernias in the abdominal wall.