Aspects of the present invention are generally directed to impedance spectroscopy in an active implantable medical device (AIMD) comprising a component with one or more electrodes. In an embodiment, the AIMD applies a signal at a plurality of frequencies using one or more of the electrodes. Measurements are then obtained for the applied signal to determine impedance(s) at the applied frequencies of the tissue in which the electrodes are located.

A method of using a computer processor for grouping prosthetic valve leaflets of an aggregate of prosthetic valve leaflets is provided. For each leaflet of the aggregate, in response to an image parameter of the leaflet, a leaflet-flexibility value is derived. At least some of the leaflets of the aggregate are designated into leaflet groups, based on similarity between the respective leaflet-flexibility value of each leaflet of the aggregate. For each of the designated leaflet groups, the flexibility value of each leaflet in the designated leaflet group is within the intra-group tolerance with respect to the leaflet-flexibility value of each other leaflet in the designated leaflet group. An indication of the designated leaflet groups is outputted. Other embodiments are also described.

Systems and methods are described for capturing images of articles under test and processing the images to automatically detect the failure of a test article. The described methods include optimizing image capture to allow for the use of low cost imaging devices instead of high speed cameras or other expensive equipment. The described methods also include several methods for processing the images to identify the occurrence of a failure event.

A presbyopia correcting system includes a test lens assembly, a controller and a dynamic lens assembly. The test lens assembly is disposed within or on an eye of a patient and includes measuring device, a transmitter and a first supporting member. The measuring device measures a pressure exerted by an ocular element of the eye and then transmits the data to the controller. A medical provider can then select an appropriate dynamic lens assembly to replace the test lens assembly. The dynamic lens assembly includes a presbyopia correcting optical element configured to change a focus with the pressure exerted by the ocular element of the eye. The dynamic lens assembly also has a second supporting member that is identical to the first supporting member. Replacing the test lens assembly with the dynamic lens assembly then corrects the presbyopia condition of or provide low vision magnification for the patient.

An optimization system for presbyopia correction includes a dynamic lens and a separately disposed controller. The dynamic lens includes a sensor measuring an ocular element of a person's eye, a control electronics, an actuator, and a presbyopia correcting optical element communicating with the actuator for its setting to a far or near optical power. The controller sends paired instructions synchronically to the person as an audio command for viewing the object at far or near distance and to the control electronics as a wireless command to send the actuation signal to the actuator for communication with the presbyopia correcting optical element. The control electronics receives the wireless command and the sensor signal, stores the sensor signal, sends the actuation signal to the presbyopia correcting optical element and stores the corresponding actuation signal. The actuation signal communicates to the presbyopia correcting optical element to set for far or near optical power.

The stent has an expansive force 0.05 N/mm or less per unit length when it has a diameter equal to the lower limit diameter of the target blood vessel and is measured under the following conditions. A radial force testing system manufactured by Blockwise Engineering LLC is used as a tester. The test conditions include a temperature of 37° C.±2° C. in the chamber of the tester; a stent diameter of 0.5 mm for start of test, and a rate of increase of diameter of 0.5 mm/s in the tester. The test method includes radially compressing the stent disposed in the chamber; recording an expansive force while gradually increasing the diameter of the chamber at the rate of increase of diameter; and dividing the expansive force by the effective length of the stent to calculate an expansive force per unit length.

A method for grouping prosthetic valve leaflets of an aggregate of prosthetic valve leaflets is provided. Using a computer processor, for each leaflet of the aggregate, in response to an image parameter of the leaflet, a leaflet-flexibility value is derived. A group size value is provided to the processor. Using the processor, at least some of the leaflets of the aggregate are designated into leaflet groups, based on similarity between the respective leaflet-flexibility value of each leaflet of the aggregate. Each of the leaflet groups includes a number of leaflets equal to the group size value. Using the processor, an indication of the designated leaflet groups is outputted. Other embodiments are also described.

A presbyopia correcting system includes a test lens assembly, a controller and a dynamic lens assembly. The test lens assembly is disposed within or on an eye of a patient and includes measuring device, a transmitter and a first supporting member. The measuring device measures a pressure exerted by an ocular element of the eye and then transmits the data to the controller. A medical provider can then select an appropriate dynamic lens assembly to replace the test lens assembly. The dynamic lens assembly includes a presbyopia correcting optical element configured to change a focus with the pressure exerted by the ocular element of the eye. The dynamic lens assembly also has a second supporting member that is identical to the first supporting member. Replacing the test lens assembly with the dynamic lens assembly then corrects the presbyopia condition of or provide low vision magnification for the patient.

A synthetic ligament made of a plurality of polymer filaments comprising two intra-osseous portions (1), within which polymer filaments are oriented only longitudinally and are woven together longitudinally and knotlessly to form a dense weave, and one intra-articular portion (2), located between the two intra-osseous portions (1), which comprises loose filaments and is untwisted around its axis. A method of producing a synthetic ligament in which the step of weaving of the polymer filaments within the intra-osseous portions (1) is carried out by means of longitudinal and knotless weaving to obtain a dense weave, with polymer filaments within the intra-articular portion (2) of a ligament remaining loose. A use of a synthetic ligament as a medical implant for the reconstruction of ligaments and tendons, notably knee ligaments.

An implantable frame comprises a plurality of corner structures configured to decrease pressure to the vessel wall and define pulsatility enhancing windows of the implantable frame. The corner structures may comprise plurality of neighboring longitudinal struts that extend in a longitudinal direction of the blood vessel when placed to form the vessel wall to a substantially polygonal cross-section and distribute pressure loading of the corner structure among the plurality of neighboring longitudinal struts to improve biocompatibility. The corner structures also allow increased forming of the vessel wall and can provide stretching of the vessel wall to enhance pulsatility of the vessel wall.