Patent classifications
C08G65/3318
TETRAHYDROFURFURYL ALCOHOL INITIALIZED POLYETHERAMINES AND USES THEREOF
The present disclosure provides a non-hydrocarbyl-based alcohol initiated polyetheramine. In particular, the polyetheramine of the present disclosure is produced from a tetrahydrofurfuryl alcohol-based initiator which is alkoxylated and then reductively aminated. The polyetheramine of the present disclosure may be used in a variety of applications, such as a raw material in the synthesis of a dispersant for use in an aqueous pigment dispersion.
Expansile crosslinked polymersome for ph-sensitive delivery of anticancer drugs
This disclosure relates to polymersomes comprising a crosslinked polymer and their use as drug delivery vehicles. Specifically, polymersomes comprising a polymer of Formula I: ##STR00001##
wherein each R is independently C.sub.1-6 alkyl; and n is an integer between 1 and 50.
POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD
Provided herein are polymeric -hydroxy aldehyde or -hydroxy ketone reagents which can be conjugated to amine-containing compounds to form stable conjugates in a single-step reaction. In selected embodiments, the polymeric reagent itself incorporates an internal proton-abstracting (basic) functional group, to promote more efficient reaction. The substituent is appropriately situated, via a linker if necessary, to position the group for proton abstraction, preferably providing a 4- or 5-bond spacing between the abstracting atom and the hydrogen atom on the -carbon. Also provided are methods of using the reagents and stable, solubilized conjugates of the reagents with biologically active compounds. In preferred embodiments, the polymeric component of the reagent or conjugate is a polyethylene glycol.
METAL OR METAL ALLOY DEPOSITION COMPOSITION AND PLATING COMPOUND
The present invention concerns a metal or metal alloy deposition composition, particularly a copper or copper alloy deposition composition, for electrolytic deposition of a metal or metal alloy layer, particularly for electrolytic deposition of a copper or copper alloy layer, comprising at least one type of metal ions to be deposited, preferably copper ions, and at least one imidazole based plating compound. The present invention further concerns a method for preparation of the plating compound, the plating compound itself and its use in a metal or metal alloy deposition composition. The inventive metal or metal alloy deposition composition can be preferably used for filling recessed structures, in particular those having higher diameter to depth aspect ratios.
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method
Provided herein are polymeric -hydroxy aldehyde or -hydroxy ketone reagents which can be conjugated to amine-containing compounds to form stable conjugates in a single-step reaction. In selected embodiments, the polymeric reagent itself incorporates an internal proton-abstracting (basic) functional group, to promote more efficient reaction. The substituent is appropriately situated, via a linker if necessary, to position the group for proton abstraction, preferably providing a 4- or 5-bond spacing between the abstracting atom and the hydrogen atom on the -carbon. Also provided are methods of using the reagents and stable, solubilized conjugates of the reagents with biologically active compounds. In preferred embodiments, the polymeric component of the reagent or conjugate is a polyethylene glycol.
EXPANSILE CROSSLINKED POLYMERSOME FOR PH-SENSITIVE DELIVERY OF ANTICANCER DRUGS
This disclosure relates to polymersomes comprising a crosslinked polymer and their use as drug delivery vehicles. Specifically, polymersomes comprising a polymer of Formula I:
##STR00001##
wherein each R is independently C.sub.1-6 alkyl; and n is an integer between 1 and 50.
Expansile crosslinked polymersome for pH-sensitive delivery of anticancer drugs
This disclosure relates to polymersomes comprising a crosslinked polymer and their use as drug delivery vehicles. Specifically, polymersomes comprising a polymer of Formula I: ##STR00001##
wherein each R is independently C.sub.1-6 alkyl; and n is an integer between 1 and 50.
FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM
A fluorine-containing ether compound represented by the following formula (1) is provided.
R.sup.2CH.sub.2R.sup.1CH.sub.2OCH.sub.2CH(OH)(CH.sub.2).sub.nCH(OH)CH.sub.2OCH.sub.2R.sup.1CH.sub.2R.sup.2(1)
(in the formula (1), n is an integer of 2 to 6, R.sup.1 is a perfluoropolyether chain, R.sup.2 is OCH.sub.2CH(OH)CH.sub.2O(CH.sub.2).sub.mOH (m in the formula is an integer of 2 to 4)).
EXPANSILE CROSSLINKED POLYMERSOME FOR PH-SENSITIVE DELIVERY OF ANTICANCER DRUGS
This disclosure relates to polymersomes comprising a crosslinked polymer and their use as drug delivery vehicles. Specifically, polymersomes comprising a polymer of Formula I:
##STR00001##
wherein each R is independently C.sub.1-6 alkyl; and n is an integer between 1 and 50.
Micellar polymer-flavonoid conjugate nanocomplex
The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent encapsulated within said micelle, where the micelle comprises a polymer-flavonoid conjugate, wherein said polymer is bonded to the B ring of said flavonoid. The micellar nanocomplex may have useful applications as a drug-delivery system.