An object of the present invention is to provide an antistatic agent which imparts excellent antistatic properties to thermoplastic resins. The antistatic agent (Z) of the present invention contains a block polymer (A) having a block of a polyamide (a) and a block of a polyether (b1) as structure units, wherein the polyether (b1) contains propylene oxide (PO) and ethylene oxide (EO) as constituent monomers, and a weight ratio of the propylene oxide (PO) to the ethylene oxide (EO), i.e., propylene oxide (PO)/ethylene oxide (EO), is 1/99 to 25/75.

The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.

A polyphenylene ether bismaleimide resin, a method for manufacturing the same, and a resin composition are provided. The polyphenylene ether bismaleimide (PPE-BMI) resin is obtained by a condensation reaction with a maleic anhydride and a primary amine compound as reactants. The primary amine compound is a polyphenylene ether diamine.

An aqueous dispersion includes precrosslinked organopolysiloxanes, emulsifiers, and water. The precrosslinked organopolysiloxanes include units of the formula R.sub.2SiO.sub.2/2 (I), and on average at least one structural unit of the formula SiR.sup.1O.sub.2/2—Y—SiR.sup.1O.sub.2/2 (III) where Y is a divalent radical of the formula —R.sup.2—[NR.sup.3—R.sup.4—].sub.nNR.sup.3—C(O)—C(O)—NR.sup.3—Z—NR.sup.3—C(O)—C(O)—NR.sup.3—[R.sup.4—NR.sup.3—].sub.nR.sup.2—.

This disclosure provides improved lipid-based compositions, including lipid nanoparticle compositions, and methods of use thereof for delivering agents in vivo including nucleic acids and proteins. These compositions are not subject to accelerated blood clearance and they have an improved toxicity profile in vivo.

A polymer hydrogel having a polymer formed by the crosslinking reaction of a polymeric unit A according to formula (I), ##STR00001##
with a crosslinking unit B according to formula (II) ##STR00002##
and water, wherein n=100-10,000, preferable 250-2500, more preferable 500-1500; m=independently 2-10, preferably 3 or 4; FG is a functional moiety that can be covalently coupled to the complementary functional moiety F1 or F2 of the crosslinking unit (B); k=0.01-0.05; h=0, 1 or 2; the spacer is an organic moiety, having a main chain comprising at least two functional moieties F1 and F2, wherein the length of the crosslinker in the extended conformation as determined by molecular modeling (including spacer and functional groups F1 and F2) is between 2.5 and 12 nm, or wherein the length is between 20 and 80 atoms.

A hydrophilic polymer derivative having a cyclic benzylidene acetal linker represented by the following formula (1):

##STR00001##

wherein R.sup.1 and R.sup.6 are each independently a hydrogen atom or a hydrocarbon group; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are each independently an electron-withdrawing or electron-donating substituent or a hydrogen atom; X.sup.1 is a chemically reactive functional group; P is a hydrophilic polymer; s is 1 or 2, t is 0 or 1, and s+t is 1 or 2; w is an integer of 1 to 8; and Z.sup.1 and Z.sup.2 are each independently a selected divalent spacer.

The present invention provides multi-armed high MW polymers containing hydrophilic groups conjugated to Factor VIII, and methods of preparing such polymers.

Provided herein is a class of reversible thermal gel polymers, formulations thereof, methods for using, and methods for making said reversible thermal gel polymers. Reversible thermal gel polymers and formulations are provided having versatile chemical, physical, mechanical and/or optical properties beneficial for a range of applications including medical treatment. In some embodiments, the architecture and composition of the polymer allows for tunable selection of one or more physical properties supporting a particular application.

A process to prepare polycarbamate comprising adding urea to a polyol in the presence of at least one catalyst selected from the group consisting of compounds having the following formula M.sub.mZ.sub.n; wherein M is a divalent metal, and Z is an anionic functionality or a functionality capable of forming a covalent bond with M and wherein n times a valence number of Z equals X and m times two equals Y wherein the absolute value of X equals the absolute value of Y is provided. Also provided are a polycarbamate produced according to the process and a coating composition comprising the polycarbamate.