A device (100) for supporting a valve annulus is described that includes spaced apart support members (105) and a connecting member (110) extending between and connecting the support members. At least one adjustor (115) is also provided that is engaged with the connecting member and can be actuated to modify a length of the connecting member between two adjacent support members. In addition, each support member may include at least two channels extending through the support members at different heights with respect to an overall thickness of the respective support member. Each channel may receive a portion of the connecting member therethrough, and each support member may further include a passageway between the channels to allow selection of one of the channels. In this way, the device may be adjusted in at least two dimensions to support the valve leaflets and promote sufficient closure of the leaflets.

An implant, disposed within a catheter, comprises a ring, anchors, and adjustment elements. The ring comprises struts arranged in a pattern of alternating peaks and troughs. Each strut has a first end-portion and a second end-portion. Each peak is defined by convergence of adjacent first end-portions disposed at an angle with respect to each other, and each trough is defined by convergence of adjacent second end-portions. Each of the anchors has a longitudinal axis, is coupled to the ring at a respective trough, and is configured to be driven along the longitudinal axis with respect to the trough and into tissue of the heart. Each of the adjustment elements is configured to adjust an angular disposition between a respective pair of the struts. A first adjustment element is coupled to its pair, and a second adjustment element is coupled to its pair distal to the first adjustment element.

Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and/or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.

The present invention relates to a prosthesis (1) for the repair of an inguinal hernia, which prosthesis (1) is intended to be implanted by a posterior or open laparoscopic route and comprises: an openworked textile (2) made of biocompatible material, comprising a first face (2a) intended to be placed facing the biological tissues of the inguinal region, and a second face (2b) arranged opposite said first face and intended to be placed facing the peritoneum, said first face being provided with fastening means that are able to fix said textile in said biological tissues of the inguinal region, characterized in that at least a part of said second face (2b) is covered with a non-porous coating (7) composed of a material that is hydrosoluble at 37 C. and non-hydrosoluble at 25 C. The invention also relates to a method for producing such a prosthesis.

An apparatus and method for delivering a prosthetic device through the vasculature of a patient includes a radially expandable member coupled to the distal end of an elongate shaft. The expandable member has an open frame configuration and an outer mounting surface for mounting the prosthetic device in a collapsed state thereon. The expandable member expands radially outwards from a first configuration to a second configuration to expand a prosthetic device mounted thereon.

A selectively expandable breast implant and method for tissue expansion are provided herein. The implant includes a flexible shell, an expandable material inside the flexible shell, and a plurality of closed conducting loops within the expandable material. The closed conducting loops absorb energy from a varying magnetic field external to the implant and generate heat, to heat the surrounding expandable material, and the expandable material expands in size based on the amount of heat generated by the closed conducting loops. The expandable material comprises a plurality of expandable microspheres that expands in response to the heat created by the closed conducting loops. The heat induction mechanism enables the closed conducting loops to generate heat for expansion of the expandable material in the implant. The implant can expand uniformly or in areas designated for selective shaping.

Accommodating intraocular (AIOL) assemblies for enabling post implantation in situ manual selective displacement of an AIOL along a human eye's visual axis relative to stationary anchor points. Axial displacement may be over a continuous range or alternatively at discrete axial stopping positions typically from about 100 ?m to about 300 ?m apart. Novels AIOLs designed to be at least partially folded for facilitating insertion into a human eye through a relatively small incision.

A two piece humeral component for use in joint arthroplasty which is adapted to be implanted into a joint and engaged by a socket component of the joint. The joint component includes a body having a first articulating surface and a second medial surface opposite the first articulating surface. The first articulating surface is adapted to be engaged by the socket and the second medial surface is adapted to be secured to mounting portion. The mounting portion has a first surface and a second medial surface. The first surface is adapted to be fixably engaged to the second mounting portion of the humeral component. The second medial surface is adapted to be secured to the humerus. A peg which has a first end adapted to engage a cavity found in the humerus is disposed on the mounting portion's second medial surface.

A delivery device for a collapsible medical device may include a handle and a delivery assembly having a compartment for receiving the medical device. A catheter member may extend from the handle to the delivery assembly. The catheter member may have a first portion with a first compliance value and a second portion with a second compliance value different from the first compliance value. An internally threaded member may be fixedly connected to the delivery assembly. An externally threaded member may have a first portion operatively connected to the actuation member and a second portion threadedly coupled to the internally threaded member so that manipulation of the actuation member causes axial movement of the compartment relative to the catheter member.

An indwelling stent is provided. The stent includes a distal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, and a proximal member that extends between a distal end portion and a proximal end portion and defines a lumen therethrough, wherein the distal member and the proximal member collectively define the stent, and wherein the distal and proximal members are discrete components and are telescopingly arranged with the distal end portion of the proximal member extending over an outer surface of the distal member.