An implant that includes a ring, anchors, and adjustment elements is advanced to a subject's heart valve. The ring includes hinges, and struts arranged in a pattern of alternating peaks and troughs. The ring circumscribes a central axis. At least one hinge is disposed at each trough. Each strut has a first end-portion and a second end-portion. Each peak is defined by convergence of adjacent first end-portions. Each trough is defined by convergence of adjacent second end-portions. Each anchor has a longitudinal axis. Within the heart, the longitudinal axis of at least one of the anchors is deflected with respect to the central axis, and each of the anchors is driven along its longitudinal axis with respect to the trough and into tissue of the heart. Subsequently, tissue of the heart is contracted by rotating the plurality of adjustment elements. Other embodiments are also described.

The present embodiments describe a multi-component endograft having a first endograft with first and second wall openings, a second endograft with a third wall opening, a third endograft with a fourth wall opening, where during an adjustment state the second and third endografts are independently adjustable, both vertically along a longitudinal axis and rotationally relative to the longitudinal axis, (1) while keeping the perimeter of the third wall opening primarily encompassed by the perimeter of the first wall opening and (2) while keeping the perimeter of the fourth wall opening primarily encompassed by the perimeter of the second wall opening.

A delivery device is configured for aligning and stabilizing a prosthetic heart valve for deployment in a native heart valve annulus. The device includes a catheter assembly having an inner shaft around which a valve compartment is defined, an outer shaft assembled over the inner shaft and adapted to slide relative to the inner shaft, a distal sheath connected to a distal end of the outer shaft and slidable therewith, an outer tube assembled over the outer shaft, and an alignment and stabilization device having a collapsed condition and an expanded condition. The outer tube is adapted to slide relative to the outer shaft to selectively cover and uncover the alignment and stabilization device.

An annuloplasty ring for repair of mitral valves whose shape can be altered remotely to perform post-implant size and/or shape adjustments. On version of the annuloplasty ring has a size-adjustable remodeling inner core within an outer suture-permeable interface for attaching the ring to an annulus. The inner core has an arcuate anterior segment that overlaps an arcuate posterior segment on opposite sides, with the segments being shaped in three dimensions to conform to the mitral annulus. The overlapping sides may have a ratchet mechanism with teeth on one engaging a detent on the other, or mating undulating bumps that can be adjusted in increments. A pair of adjustment filaments that pass through a delivery system and through channels in one segment may act on the other segment to adjust the peripheral shape of the annuloplasty ring.

Devices, methods, and computer program products are provided herein for hearing safety. An example hearing safety device configured to be worn by a user includes an earmuff body that defines an interior cavity configured to receive the user's ear therein when worn by the user and an exterior surface opposite the interior cavity. The hearing safety device includes an ear lid attached to a surface of the interior cavity. The ear lid projects into the interior cavity from the surface of the interior cavity and defines a sealing surface configured to substantially seal an ear canal of the user's ear when the hearing safety device is worn by the user. The hearing safety device also includes an adjustment mechanism operably attached to the ear lid and configured to move the ear lid relative the interior cavity of the earmuff body.

Apparatus and methods are provided to position a device at adjacent tissues near a urethra to overcome the problem of urine leakage during physical movement or activity by changing a contour of a urethra. The devices may include mechanisms such as an inflatable pouch or a pillow anchored to the adjacent tissues of a urethra by an anchoring hook. The inflation of the pouch by an external fluid flexes the pouch towards a urethra and changes the contour of the urethra. The devices may also or alternatively include one or more tissue grasping T-fasteners having forward-facing and reverse-facing barbs to anchor the tissues adjacent to a urethra and bend the contour of the urethra. The device may also include actuators, clips or spring jacks having inflatable bands. The device may include a cap, one-way valves and a combination of a plug and cap to block urethral ostium to temporarily block urine flow from a bladder.

A device (100) for supporting a valve annulus is described that includes spaced apart support members (105) and a connecting member (110) extending between and connecting the support members. At least one adjustor (115) is also provided that is engaged with the connecting member and can be actuated to modify a length of the connecting member between two adjacent support members. In addition, each support member may include at least two channels extending through the support members at different heights with respect to an overall thickness of the respective support member. Each channel may receive a portion of the connecting member therethrough, and each support member may further include a passageway between the channels to allow selection of one of the channels. In this way, the device may be adjusted in at least two dimensions to support the valve leaflets and promote sufficient closure of the leaflets.

Provided herein is a system including, in some embodiments, a stent and a catheter. The stent includes a number of filaments arranged to form a tubular body of the stent, a number of microcells forming each filament of the number of filaments, and a port in an end portion of the stent. Each microcell includes a moveable microsurface. The port of the stent may be configured to accept power and control signals for moving the microsurfaces. The catheter may include a cable configured to connect with the port of the stent and provide the power and the control signals for moving the microsurfaces. Moving the microsurfaces may include matching a shape of an anatomical vessel to maintain patency thereof while mitigating stress on the anatomical vessel.

A replacement heart valve implant defining a central longitudinal axis extending from an upstream end to a downstream end may include an expandable anchor member configured to shift between a delivery configuration and a deployed configuration, a circumferential support member distinct from and attached to the expandable anchor member, at least a portion of the circumferential support member extending downstream of the expandable anchor member, and a plurality of valve leaflets secured to the expandable anchor member. The plurality of valve leaflets may include a valve leaflet commissure movable from a first longitudinal position relative to the downstream end in the delivery configuration to a second longitudinal position relative to the downstream end in the deployed configuration.

The present invention relates to surgical implants with adjustable size features, and methods for treating pelvic conditions by use of the implants.