Various examples address support structures (e.g., prosthetic valve support structures or frames) that incorporate a frame that, upon transitioning to a deployed configuration, include a proximal section has increased stiffness, or resistance to deformation in a transverse plane to a longitudinal axis of a device, including resistance to a change in shape, size, or both. Such an increase in transverse deformation resistance may be measured as an increase in radial compressive resistance or an increase in flat plate stiffness, for example, or both. Such increases in transverse deformation resistance may be realized through a reduction in length of the increased stiffness region of the support structure, such as through longitudinal compression of the region following an initial radial expansion of the region.

The invention relates to an intraocular lens comprising an optics body and a haptic which has a first component with a latching protrusion and a second component with a latching recess, the latching protrusion and the latching recess being arranged at a distance from one another when the haptic is arranged in a relaxed state and being configured to engage with one another when, proceeding from the relaxed state, the haptic is moved in the direction of the optics body into a completely compressed state of the haptic via a partially compressed state of the haptic, the haptic being formed by a single piece and having a haptic cutout which is delimited by the first component and the second component.

Embodiments disclosed herein may be directed to devices, systems, and methods for addressing leaflets within a patient's body, including displacement of such leaflets. The leaflets may be of a native heart valve, or may be of a prosthetic heart valve that has been previously implanted within the patient's body. The leaflets may be displaced to reduce the possibility of the leaflets blocking access to structures within the patient's body, which may comprise cardiac structures such as coronary ostia, for example. As such, a reduced possibility of maladies caused by blockage of the cardiac structures may result.

Prosthetic implant systems for diameter adaptation may be provided. The systems may provide for increased flexibility of providing implants having various diameters, and reducing expense associated with keeping a stock of implants at various sizes. Embodiments as disclosed herein may utilize a prosthetic implant having a docking frame that may be configured to expand to a range of working diameters. The docking frame may dock with a valve frame that may be configured to expand to a working diameter that is more closely tailored to the diameter of the implantation site. The valve frame may have a lesser range of expansion of working diameters than the docking frame.

This disclosure relates generally to prosthetic valves and methods and systems for deploying, positioning, and recapturing the same. A prosthetic valve includes one or more support structures. At least one of the one or more support structures defines an elongate central passageway of the prosthetic valve. The prosthetic valve can also include a plurality of leaflet elements attached to at least one of the one or more support structures and disposed within the elongate central passageway for control of fluid flow through the elongate central passageway. At least one of the one or more support structures is configured to biodynamically fix the prosthetic valve within a native valve such as, for example, a native tricuspid valve of a heart.

A prosthetic heart valve system includes a collapsible and expandable outer frame extending from an atrial end to a ventricular end, the atrial and ventricular ends coupled by a central portion, the outer frame including a plurality of suture receiving rings formed around a circumference of the ventricular end. The system further includes a collapsible and expandable inner frame positioned radially inward of and coupled to the outer frame. The system further includes a prosthetic valve assembly coupled to, and positioned radially inward of, the inner frame, and a strand extending from a first free end to a second free end. A middle portion of the strand passes through each of the suture receiving rings in a delivery configuration of the prosthetic heart valve system. The first and second free ends are configured to be pulled simultaneously by a user to radially collapse the ventricular end of the outer frame.

A dual opposing helical stent having a furled, small-diameter state and an expanded, large-diameter state. In the furled, small-diameter state, the stent includes a plurality of central lobes arranged at spaced-apart intervals and extending longitudinally defining a stent axis. The stent also includes peripheral lobes formed on the plurality of central lobes. The terminal ends of the stent are welded in a middle section of the stent. A method and technique for manufacturing the stent is also disclosed.

A system for reducing regurgitation includes a catheter and a coaptation member disposed along a distal end portion of the catheter, wherein the coaption member is sized to be advanced through a patient’s vasculature in a compressed configuration and wherein the coaptation member is expandable for deployment between leaflets of a native tricuspid valve. The coaptation member includes a frame covered with one or more panels of bioprosthetic tissue or flexible polymer to form a three-sided shape having three convex sides separated by rounded corners. An anchor is coupled to a proximal end portion of the catheter and is shaped for attachment to a vessel wall. After deployment, the anchor secures the position of the coaptation member relative to the native tricuspid valve.

An implantable device delivery system is disclosed. The delivery system includes a constraining member situated between an interior layer and an exterior layer of a cover. The interior layer of the cover is disposed about an implantable medical device, and the exterior layer of the cover extends over a portion of the interior layer. The cover is generally tapered to minimize deployment forces. The constraining member is disposed about a portion of the interior layer and operates to constrain the implantable device to a delivery configuration. The cover and the constraining member are generally configured to be removed concurrently during deployment of the implantable device.

An intraocular lens system for implantation in an eye is provided. The intraocular lens system includes a ciliary body implant having a passive ciliary signal element, the ciliary body implant being implantable in the eye such that the ciliary signal element provides a ciliary signal in response to a movement of the ciliary muscle of the eye. The intraocular lens system also includes an intraocular lens having a sensor element for receiving the ciliary signal. The ciliary body implant and the intraocular lens are formed separately from each other and the intraocular system is configured to control a refractive effect of the intraocular lens that is dependent on the ciliary signal received from the sensor element.