Devices and methods are disclosed for the treatment or repair of regurgitant cardiac valves, such as a mitral valve. An annuloplasty device can be placed in the coronary sinus to reshape the mitral valve and reduce mitral valve regurgitation. A protective device can be placed between the annuloplasty device and an underlying coronary artery to inhibit compression of the underlying coronary artery by the annuloplasty device in the coronary sinus. In addition, the protective device can inhibit compression of the coronary artery from inside the heart, such as from a prosthetic mitral valve that exerts radially outward pressure toward the coronary artery. The annuloplasty device can also create an artificial inner ridge or retaining feature projecting into the native mitral valve region to help secure a prosthetic mitral valve.

Disclosed in the present disclosure is a prosthetic heart valve comprising a universal core which can be universally used in different implantation positions and different application scenarios, and an adapter selected from more than one adapters which are respectively suitable for the different application scenarios. The prosthetic heart valve according to the present disclosure has better flexibility and wider application range compared with various existing prosthetic heart valves, and may save time cost and research and development cost.

A collapsible and expandable prosthetic heart valve stent is provided and comprising an outer section, a valve support defining a flow channel therethrough, a transition section configured to smoothly transition the outer section to the valve support. The valve support is disposed within an interior defined by the outer section, with the inflow end of the valve support disposed inside the outer section's interior. In some cases, the outflow end of the valve support is at least partially defined by the transition section. The prosthetic leaflets are disposed on the inner surface of the valve support's flow channel and are located at or above the annulus of the heart chamber. A prolapse prevention system is attached to the stent to mitigate native valve leaflet prolapse.

The embodiments of the present disclosure provide an interventional valve stent and an aortic valve. The interventional valve stent may include a valve stent defining a frame lumen. The valve stent may include straight rods connecting an upstream port and a downstream port, and oblique rods connected between the straight rods. An upstream section, a midstream section, and a downstream section may be sequentially formed along a direction from the upstream port to the downstream port. When the valve stent expands from a compressed state to an expanded state, an expansion strain provided by the oblique rods located in the midstream section to a circumferential direction of the valve stent may be greater than an expansion strain provided by the oblique rods located in the upstream section and/or the downstream section to the circumferential direction of the valve stent to compensate for a rate difference between a rate of circumferential expansion of the midstream section and a rate of circumferential expansion of the upstream section and/or a rate of circumferential expansion of the downstream section.

Improvements to devices, systems, and methods for delivering and/or deploying an implantable medical device are described. An implantable medical device may include an annuloplasty ring for implantation on a valve of a patient. Systems and methods may be configured to present graphical user interfaces with device images to implement efficient and accurate implantation of the implantable medical device. The device images may be based on sensor information obtained via sensors associated with the implantable medical device, such as a camera device, a diagnostic imaging device, position sensors, and/or the like. In other aspects, systems and methods may determine optimized configurations for the implantable medical device based on device characteristics including, without limitation, a shape formed by components of the implantable medical device and/or component coordinate information. Systems and methods may operate to facilitate deployment of the implantable medical device to correspond with the optimized configuration. Other embodiments are described.

An apparatus for hydraulic deployment and recapture of an implant includes a hydraulic implant uncovering mechanism and a hydraulic implant re-covering mechanism. The implant uncovering mechanism and the implant re-covering mechanism are independently actuateable with a fluid, and the implant uncovering mechanism is coupled to the implant re-covering mechanism by a flexible elongate tether.

A medical implant including an expandable framework configured to shift between a collapsed configuration and an expanded configuration, the expandable framework comprising a plurality of interconnected struts defining a plurality of cells; and an occlusive element connected to the expandable framework and having an inner surface and an outer surface. The expandable framework may include a plurality of securement members projecting from the plurality of interconnected struts. One of the inner surface or the outer surface of the occlusive element may be in contact with the plurality of interconnected struts, and the other of the inner surface and the outer surface not in contact with the plurality of interconnected struts may lie against an opposing surface of each of the plurality of securement members. A tip portion of the plurality of securement members may not extend radially outward of the plurality of interconnected struts.

A method of providing support in an aortic region. The method includes wrapping a landing band around an outside of a portion of an aortic vessel in a vicinity of a sinotubular junction (STJ) to form a wrapped portion of the aortic vessel. The method further includes securing the landing band to form a secured landing band. The method also includes endovascularly delivering a stent graft in a radially constricted configuration into the aortic vessel. The method also includes deploying the stent graft to a radially expanded configuration such that the stent graft contacts the wrapped portion of the aortic vessel. The method also includes connecting the stent graft in the radially expanded configuration to the secured landing band.

Disclosed herein are embodiments related to a method for performing a minimally invasive procedure, the method including delivering an annuloplasty ring in a linear shape using a delivery system. In some embodiments, the delivery of the annuloplasty ring may utilize a trans-septal approach or a trans-apical. In some embodiments, the delivery system may position the annuloplasty ring using a flexible stabilizing mechanism and/or activate one or more anchors to extend outward from the annuloplasty ring.

A method includes advancing a delivery assembly through a patient's vasculature toward a native heart valve of the patient, wherein the delivery assembly comprises a first catheter assembly and a second catheter assembly extending through a shaft of the first catheter assembly, and wherein a support member is in an uncoiled, elongated configuration within a sheath of the first catheter assembly. The support member is deployed from the sheath by pushing the second catheter assembly distally relative to the first catheter assembly so that the support member is uncovered by the sheath and the support member extends around native chordae tendineae and/or native leaflets of the native heart valve. A prosthetic valve is implanted within the native leaflets of the native heart valve such that the native chordae tendineae and/or native leaflets are frictionally engaged between the support member and the prosthetic valve.