A prosthetic heart valve includes an expandable annular frame having an inflow end, an outflow end, an interior, an exterior, a plurality of openings, and a longitudinal axis; a plurality of commissure supports members outside of the frame; and a plurality of quadrilateral valve leaflets each having a main body having an inflow edge and an outflow edge, and a pair of opposing leaflet tabs extending from opposite sides of the main body, each leaflet tab being paired with an adjacent leaflet tab of an adjacent leaflet, each pair of leaflets tabs extending through a respective opening of the frame and coupled to one of the commissure supports to form a commissure tab assembly, wherein each commissure tab assembly is located on the exterior of the frame and the main body of each leaflet is located on the interior of the frame.

In particular, some embodiments provide shunts having a plurality of individually actuatable flow control elements that can control the flow of fluid through associated ports and/or flow lumens. For example, each individually actuatable flow control element can be actuated to modify a flow of a corresponding port and/or flow lumen. The individually actuatable flow control elements may be actuated along a given actuation axis. A flow control assembly may include a plurality of flow control elements arranged about a collection region. Accordingly, the shunts described herein can be manipulated into a variety of configurations that provide different drainage rates based on a degree to which the ports and/or flow lumens are blocked or unblocked, therefore providing a titratable glaucoma therapy for draining aqueous from the anterior chamber of the eye.

The present technology is directed to adjustable flow glaucoma shunts and methods for making and using such devices. In many of the embodiments described herein, the shunts include a generally flat frame. The frame can include an elongated portion having a lumen extending therethrough and a bladder portion defining an interior chamber that is in fluid communication with the lumen. When implanted in a patient's eye, aqueous can drain from the anterior chamber to a target outflow location via the lumen and interior chamber. In some embodiments, the shunts include a flow control assembly positioned within the interior chamber of the bladder portion to control the flow of aqueous through the lumen.

In a representative embodiment, a method comprises implanting first and second inflatable bodies within an annulus of a native heart valve by securing the inflatable bodies to tissue of the native heart valve with sutures, and implanting a prosthetic heart valve between the inflatable bodies such that the prosthetic heart valve is retained within the annulus by the inflatable bodies.

The present technology is directed to implantable medical devices for draining fluid from a first body region to a second body region. Some embodiments of the present technology provide adjustable devices that are selectively titratable to provide various levels of therapy. For example, the adjustable devices can have a drainage element with a lumen extending therethrough, a flow control element, and an actuation assembly. The actuation assembly can drive movement of the flow control element to change a dimension of and/or a flow resistance through the lumen, thereby increasing or decreasing the relative drainage rate of aqueous from an eye. In some embodiments, the actuation assembly and the flow control element together operate as a ratchet mechanism that can selectively move the flow control element between a plurality of positions and lock the device in a desired configuration until further actuation of the actuation assembly.

The present invention relates to an anti-reflux valve for preventing gastro-esophageal reflux disease and includes a body formed in a ring shape and fixed to an upper end of a gastro-esophagus; a reflux blocking plate coupled to an inner circumferential surface of the body to be rotatable in one direction; and a fixing clip coupled to an outer circumferential surface of the body to fix the body to the upper end of the gastro-esophagus.

An implantable constriction device (10) for constricting a urethra (U) of a patient. The implantable constriction device (10) comprises at least one operable hydraulic constriction element (101a) configured to be inflated to constrict the urethra (U) for restricting the flow of urine therethrough, and a controller for controlling the inflation of the at least one operable hydraulic constriction element (101a).

A method for setting a fill level of a liquid balloon (1) is provided, in which the volume of a liquid-filled receiving space (10) of a pump unit (5) is changed by moving an actuating part (11) of the pump unit (5) by an electric motor (6) which is fed by a battery (7). An actuating process of the actuating part (11) is carried out by a control unit (8) which controls the electric motor (6). The actuating process includes travel control of the actuating part (11) for approaching a target position of the actuating part (11) and after this travel control a check as to whether the pressure of the liquid in the receiving space (10) lies within a permissible filling pressure range around the second filling pressure. If necessary, the position of the actuating part (11) is adjusted.

A device including a liquid balloon (1), a pump unit (5) connected to the liquid balloon (1) via a first connection line (3) for pumping liquid into the liquid balloon (1) and for pumping liquid out of the liquid balloon (1), an electric motor (6) for driving the pump unit (5), a battery (7) for supplying energy to the electric motor (6) and an electronic control unit (8) for controlling the electric motor (6). The device further includes a manual actuating unit (51) for removing liquid from the liquid balloon (1) and for pumping liquid back into the liquid balloon (1), the manual actuating unit (51) having a flexible pump body (30) which is connected to the liquid balloon (1) via a second connection line (31).

The present invention relates to an artificial bladder system having a double space divided by a partition wall and a wireless, non-powered urine fullness sensor using an RFID technology, which provides an artificial bladder system comprising: an outer wall that forms the outer shape of the artificial bladder, is inserted into the body, and has an inner space; a partition wall, wherein both ends are fixed to the inside of the outer wall, the inner space of the outer wall is divided into a double space of a urine reservoir and a working fluid space, and it is deformable according to amounts of the urine and the working fluid; and a urine fullness sensor installed in the working fluid space and sensing a urine fullness degree based on the deformation of the partition wall.