An implanted intraocular shunt can be manually manipulated, without surgical intervention, to modify the flow resistance of the shunt, thereby providing relief from high intraocular pressure while avoiding hypotony. For example, through application of pressure along a surface of the eye, a portion of the shunt can be displaced or separated relative to the shunt, thereby decreasing a flow resistance of the shunt.

A medical device for shutting off a body channel is provided including a band section that can be placed around the body tissue surrounding a body channel and can be closed to form a ring enclosing a passage opening for the body tissue, and has a cavity which makes up one part of a working fluid receiving chamber of the device, for receiving working fluid, and a pump unit for conveying the working fluid. The passage opening is made smaller by introducing the working fluid into the cavity. The arrangement also includes a storage container that has a flexible wall which delimits a storage chamber, wherein to apply an additional force to the body tissue guided through the passage opening, the volume of the storage chamber is made smaller by increasing an ambient pressure acting on the storage container, and the wall of the storage container is at least substantially non-extensible.

An ocular implant including an intraocular pressure sensor and having an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the Schlemm's canal portion being arranged and configured to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.

A medical device for narrowing or closing an anatomical channel includes a band part (1) which can be placed around the body tissue (2) surrounding the anatomical channel and which can be closed to form a ring that encloses a through-opening (6) for the body tissue, wherein the band part (1) has a hollow chamber (3), and wherein the through-opening (6) can be made smaller by introducing a fluid into the hollow chamber (3). The medical device moreover includes a pump unit (10) which serves to convey the fluid and which has an electric drive (15) controllable by an electronic control system of the device, wherein a pressure value corresponding to the pressure of the fluid in the hollow chamber (3) or dependent on this pressure can be detected by the electronic control system. The device moreover has an air pressure sensor (23) for detecting the atmospheric pressure.

According to an aspect, an implant includes an inflatable member and a pump assembly configured to facilitate a transfer of a fluid from the reservoir to the inflatable member. The inflatable member has a sidewall that defines a lumen and an elongate member disposed within the lumen.

Various aspects of the present disclosure are directed toward apparatuses, systems and methods that include arranging an acute alteration of blood flow in, for example, heart failure patients.

The present technology is directed to implantable medical devices for draining fluid from a first body region to a second body region. Some embodiments of the present technology provide adjustable devices that are selectively titratable to provide various levels of therapy. For example, the adjustable devices can have a drainage element with a lumen extending therethrough, a flow control element, and an actuation assembly. The actuation assembly can drive movement of the flow control element to change a dimension of and/or a flow resistance through the lumen, thereby increasing or decreasing the relative drainage rate of aqueous from an eye. In some embodiments, the actuation assembly and the flow control element together operate as a ratchet mechanism that can selectively move the flow control element between a plurality of positions and lock the device in a desired configuration until further actuation of the actuation assembly.

An external ear canal pressure regulation device including a fluid flow generator, an earpiece having an axial earpiece bore, and a valved conduit fluidicly coupled to the fluid flow generator and the axial earpiece bore, whereby the earpiece has a compliant earpiece external surface configured to sealably engage an external ear canal as a barrier between an external ear canal pressure and an ambient pressure.

According to an aspect, an inflatable penile prosthesis includes a reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to facilitate a transfer of a fluid from the reservoir to the inflatable member. The pump assembly includes a pump bulb, and a valve body defining a fluid passageway. The valve body includes a refill valve disposed in the fluid passageway. The refill valve includes a valve member. In response to the pump bulb being compressed, the valve member moves within the fluid passageway in a first direction to a closed position in which the valve member blocks the fluid from being transferred around the refill valve. In response to the pump bulb being uncompressed, the valve member moves within the fluid passageway in a second direction to an open position in which the valve member allows the fluid to transfer around the refill valve.

An implantable inflatable device includes a fluid reservoir defining a cavity, an inflatable member, a pump assembly configured to transfer fluid from the fluid reservoir to the inflatable member, and a programmable control module, the programmable control module being configured activate the pump assembly to transfer fluid from the fluid reservoir to the inflatable member.