An annuloplasty ring is provided including a core defining a closed ring and comprising one or more flexible portions, wherein the core is capable of deformation about the flexible portion between a first configuration and a second configuration upon application of a predetermined force; a resilient intermediate layer; and a fabric cover layer.

The present invention relates to a ring-shaped implant having shape memory for implantation in the cornea of the eye, wherein the implant spans an implant plane in a starting state, and wherein the implant is transferable by application of a compression force (F) in the implant plane (8) from a starting state into an intermediate state, in which the lateral dimensions of the implant, measured in the force direction, are smaller than in the starting state, wherein it is provided according to the invention that the alignment of an implant cross-section (1) in the intermediate state is pivoted at least in one pivotable longitudinal section of the implant by an angle (α) in relation to the starting state.

Compliance control stitch patterns sewn or embroidered into biotextile or medical textile substrates impart reinforcing strength, and stretch resistance and control into such substrates. Compliance control stitch patterns may be customizable to particular patients, substrate implantation sites, particular degenerative or diseased conditions, or desired time frames. Substrates having compliance control stitch patterns sewn or embroidered into them may be used in tissue repair or tissue reconstruction applications.

A system has a heart valve assembly that includes a stent-frame having an anchoring section and an outflow section, with the anchoring section having a distal annulus section and a support section that is positioned between the distal annulus section and the outflow section. The distal annulus section has a concave inflection. A leaflet assembly is stitched to the anchoring section. The system also includes a balloon on which the heart valve assembly is crimped, the balloon having a central valve contact portion that has an outflow portion, a neck portion, and a central portion between the outflow portion, and the neck portion. The outflow portion of the balloon receives the outflow section of the stent-frame, the central portion of the contact portion of the balloon receives the support section of the stent-frame, and the neck portion receives the annulus section of the stent-frame.

A medical arrangement is configured to introduce an object, such as an implant, from a distal end into an anatomical target position. The medical arrangement comprises a first introducer having distal and proximal ends, and a second introducer having distal and proximal ends. The first introducer is an outer introducer and said second introducer is configured to be operated inside and guided by said first introducer. At least a portion of the first introducer is configured to take a first curved shape, and at least a portion of the second introducer is configured to take a second curved shape. The portion of the second introducer configured to take said second curved shape comprises a tubular member inside said second introducer for enabling introducing of the object or implant through said tubular member and thereby over at least said second curved shape of said second introducer.

A device includes a first end portion, a second end portion, an intermediate portion, and a graft material. The first end portion has a first end diameter. The second end portion has a second end diameter smaller than the first end diameter. The first end portion comprises a first material. The second end portion comprises a second material different than the first material. The intermediate portion is between the first end portion and the second end portion. The intermediate portion tapers between the first end portion and the second end portion. The graft material is coupled to at least the intermediate portion.

Embodiments of the present disclosure are directed to delivery systems, devices and/or methods of use to deliver and/or controllably deploy an implant in the form of a prosthesis, such as but not limited to a replacement heart valve, to a desired location within the body. In some embodiments, a replacement heart valve and methods for delivering a replacement heart valve to a native heart valve, such as a mitral valve, are provided. Features of delivery systems are disclosed, as well as echogenic markers for delivery systems.

A system has a heart valve assembly that includes a stent-frame having an anchoring section and an outflow section, with the anchoring section having a distal annulus section and a support section that is positioned between the distal annulus section and the outflow section. The distal annulus section has a concave inflection. A leaflet assembly is stitched to the anchoring section. The system also includes a balloon on which the heart valve assembly is crimped, the balloon having a central valve contact portion that has an outflow portion, a neck portion, and a central portion between the outflow portion, and the neck portion. The outflow portion of the balloon receives the outflow section of the stent-frame, the central portion of the contact portion of the balloon receives the support section of the stent-frame, and the neck portion receives the annulus section of the stent-frame.

Provided is a delivery shaft assembly (200) having a proximal end (20) and a distal end (40) for delivery of an ocular implant (230), wherein: delivery shaft assembly (200) comprises a delivery shaft (220) having a lumen (222) configured for holding the implant (230), and an adapter (210) at the proximal end (20) of the delivery shaft (220) configured for attachment to an inserter tool (500) for deployment of the implant (230); the delivery shaft (220) comprises a distal compliant section (244) that is repeatably bendable, compliant, and biased in a curve in a 1st plane (60); the delivery shaft (220) is provided with an axially longitudinal observation fenestration (258) allowing visualisation of the implant (230) from an anterior (52) side of the delivery shaft (220); the delivery shaft (220) comprises a distal tip section (246) having an atraumatic pointed end; the delivery shaft (220) is formed from a compliant material formed into a bend-resistive tube (250), and a wall (224) of the tube (250) in the distal compliant section (244) is provided with a plurality of flexibility slots (252) and/or flexibility apertures (256-b) that impart the bendability.

A transcatheter prosthetic heart valve includes a stent frame and a leaflet material. The stent frame includes a top portion and a bottom portion. The leaflet material includes a lower portion attached to the stent frame and an upper portion that includes leaflets capable of moving between an open configuration and a closed configuration. At least a portion of the leaflet material weaves through the stent frame. The transcatheter prosthetic heart valve also includes one or more reinforcement components coupled to the stent frame and/or to the leaflet material to enhance performance of the transcatheter heart valve.