An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves. Cable allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. Stranded cable provides a MIS annuloplasty ring with sufficient flexibility in the x-y plane to allow a surgeon to squeeze the ring into a small incision, such as being able to pass through an 18 Fr or smaller catheter, while maintaining structural rigidity under forces exerted on the implanted ring by the cardiac cycle. The particular shape of the annuloplasty ring is fixed using a heat setting process.

Implantable in vivo sensors used to monitor physical, chemical or electrical parameters within a body. The in vivo sensors are integral with an implantable medical device and are responsive to externally or internally applied energy. Upon application of energy, the sensors undergo a phase change in at least part of the material of the device which is then detected external to the body by conventional techniques such as radiography, ultrasound imaging, magnetic resonance imaging, radio frequency imaging or the like. The in vivo sensors of the present invention may be employed to provide volumetric measurements, flow rate measurements, pressure measurements, electrical measurements, biochemical measurements, temperature, measurements, or measure the degree and type of deposits within the lumen of an endoluminal implant, such as a stent or other type of endoluminal conduit. The in vivo sensors may also be used therapeutically to modulate mechanical and/or physical properties of the endoluminal implant in response to the sensed or monitored parameter.

The present disclosure describes intraluminal support devices having high radial stiffness regions with smaller diameter and low radial stiffness regions with larger diameter. When deployed to the vasculature of a patient in need of treatment, the high radial stiffness region is sized such that it has approximately the diameter of the vessel in need of treatment, so that it produces substantially zero chronic radial force when the vessel is not being subjected to external compression. The low radial stiffness regions anchor the device to the vessel wall and provide a less-abrupt transition from the high radial stiffness structure. Methods of making and using such devices are also described.

The present invention discloses a left ventricular outflow tract stent and a delivery system. The left ventricular outflow tract stent includes a stent body, the stent body is composed of a plurality of supporting components arranged along a first path coinciding with a left ventricular outflow tract path, each of the supporting components includes an inverted-V-shaped frame and an inverted-trapezoidal frame, and the inverted-V-shaped frames and the inverted-trapezoidal frames are alternately arranged to form peak regions and valley regions; connecting strips are arranged on the supporting components; and the stent delivery system includes a control component, a delivery catheter, an air bag component, a guide component, and a loading component, the air bag component is connected with the control component through the delivery catheter, the guide component is arranged at an end of the air bag component, away from the delivery catheter, and the loading component is arranged at an end of the guide component away from the air bag component. The control component is configured to control the delivery system to accurately carry and release the stent body on the loading component to a proper position of the left ventricular outflow tract, so that the safety of a minimally invasive surgery is improved.

An intravascular emboli capture and retrieval system for intravascular embolism protection and embolism removal or maceration. Guidewire mounted proximally and distally located multiple opening filters are deployed within the vasculature and used to part, divide and macerate embolic debris and to capture such embolic debris within the confines thereof. A deployable flexible preformed memory shaped capture sleeve is alternatively used to collapse one or more filters and embolic debris therein for subsequent proximal withdrawal from the vasculature.

An implantable expandable medical device in which selected regions of the device are in a martensite phase and selected regions are in an austenite phase. The martensitic regions exhibit pseudoplastic behavior in vivo and may be deformed without recovery under in vivo body conditions. In contrast the austenitic regions exhibit superelastic behavior in vivo and will recover their pre-programmed configuration upon deformation or release of an applied strain.

An annuloplasty repair segment for heart valve annulus repair and a method for forming. A multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves which allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. The particular shape of the annuloplasty ring is fixed using a heat setting process including heating the flexible core member to a temperature higher than 500 C. and holding it in a desired heat-set saddle shape for a period of time. The core is then rapidly cooled to impart physical properties such that the flexible core member can be straightened, during implantation, to fit through a tubular access device and regain the heat-set saddle shape after exiting the access device and, when attached to the native heart valve, the flexible core member is strong enough to remodel the native heart valve.

The present invention discloses a left ventricular outflow tract stent and a delivery system. The left ventricular outflow tract stent includes a stent body, the stent body is composed of a plurality of supporting components arranged along a first path coinciding with a left ventricular outflow tract path, each of the supporting components includes an inverted-V-shaped frame and an inverted-trapezoidal frame, and the inverted-V-shaped frames and the inverted-trapezoidal frames are alternately arranged to form peak regions and valley regions; connecting strips are arranged on the supporting components; and the stent delivery system includes a control component, a delivery catheter, an air bag component, a guide component, and a loading component, the air bag component is connected with the control component through the delivery catheter, the guide component is arranged at an end of the air bag component, away from the delivery catheter, and the loading component is arranged at an end of the guide component away from the air bag component. The control component is configured to control the delivery system to accurately carry and release the stent body on the loading component to a proper position of the left ventricular outflow tract, so that the safety of a minimally invasive surgery is improved.