An implantable prosthetic device comprises a frame comprising a first set of first struts and a second set of second struts. The first struts are pivotably connected to each other at a plurality of distal and proximal apices at distal and proximal ends of the frame. The second struts are pivotably connected to each other at a plurality of distal and proximal apices at the distal and proximal ends of the frame. The first struts have a first thickness, and the second struts have a second thickness, wherein the first thickness is greater than the second thickness. One or more actuators are coupled only to one or more corresponding pairs of a distal apex and a proximal apex formed by the first struts, wherein the one or more actuators are configured to apply axially directed forces to the frame to radially expand the frame.

A transcatheter valve assembly replacement device includes an improved paravalvular seal.

A percutaneous heart valve delivery system including a valve delivery catheter coupled with a first inflatable balloon positioned at a distal end of the valve delivery catheter, wherein the first inflatable balloon is configured to fracture a previously implanted prosthetic heart valve; and a replacement transcatheter heart valve positioned proximal to the first inflatable balloon, wherein the replacement transcatheter heart valve is configured to be implanted subsequently within the previously implanted, fractured prosthetic heart valve, following fracture of the previously implanted heart valve without withdrawal of the percutaneous heart valve delivery system. Also disclosed are methods of implantation of a new heart valve within a previously implanted prosthetic heart valve and methods of valvuloplasty of a native heart valve.

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

This disclosure is directed to a docking device for a prosthetic heart valve. The docking device includes an inflow end, an outflow end, a support structure disposed between the inflow end and the outflow end, and an expandable sleeve. The support structure includes inflow and outflow sections that are configured to be positioned on inflow and outflow sides, respectively, of a native heart valve. The outflow section includes a first portion, a second portion, and a third portion, wherein the first portion is disposed closer to the inflow section than the second portion, and wherein the third portion is disposed between the first and second portions. The expandable sleeve may extend at least 100 degrees over the first portion of the outflow section of the support structure. Additionally, or alternatively, the first portion of the outflow section of the support structure may have a different geometry than the third portion.

A prosthetic heart valve may include an expandable stent having a plurality of struts forming cells connected to one another in a plurality of annular rows around the stent, a cuff attached to an annulus section of the stent by cuff sutures that have a plurality of stitches extending through material of the cuff and looping around the struts, and a plurality of leaflets each having a belly attached to the cuff within an interior region of the stent. The leaflets may together have a coapted position occluding the interior region of the stent and an open position in which the interior region is not occluded. The belly of each leaflet may be attached to the cuff by leaflet sutures extending in a path that crosses some of the struts in overlap zones. Those struts may be devoid of the stitches within the overlap zones.

A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.

A stent 1 which is inserted into a catheter and extruded from the catheter into a blood vessel to dilate a blood vessel, wherein the stent is equipped with a first stent body 10 in which a plurality of first cells comprising struts arranged in a frame shape are spread in the circumferential direction and are contiguous in the central axial direction and a second stent body 20, interpolated into the first stent body, in which a plurality of second cells comprising struts arranged in a frame shape are spread in the circumferential direction and are contiguous in the central axial direction, and, in a state in which the second stent body 20 is interpolated into the first stent body 10, the intersecting portions of the second cells are arranged in the hole portions of the first cells and the first stent body 10 and the second stent body 20 are not connected to each other in the radial direction.

An intraluminal prosthesis (100) and methods thereof for treating at least portal hypertension. The intraluminal prosthesis (100) includes a mixed frame of a main frame (110) and a terminal frame (120), as well as a tubular graft (130) over at least the main frame (110). The main frame (110) includes a plurality of annular members (112). Each annular member (112) includes a plurality of diamond-shaped cells (114). The terminal frame (120) includes woven struts (122). The terminal frame (120) includes a coupled end (124) coupled to at least one of a first-end annular member (112a) or a second-end annular member (112b) respectively at a first end (110a) or a second end (110b) of the main frame (110). The tubular graft (130) extends from the first-end annular member (112a) to the second-end annular member (112b). The intraluminal prosthesis (100) includes an insertion state for inserting the intraluminal prosthesis (100) and an expanded state for use of the intraluminal prosthesis (100) is in use.

The present disclosure provides a pulmonary artery stent. The pulmonary artery stent includes: a metal stent capable of circumferential expansion; and an isolation membrane wrapping the metal stent to isolate the metal stent from an external environment, and the isolation membrane having a circumferential tensile strength less than an axial tensile strength. The embodiments of the present disclosure can not only expand the diameter of the stent according to a change in the diameter of a blood vessel to meet a support performance requirement after the blood vessel enlarges but also isolate the metal portion of the stent from a vascular environment, thus effectively solving a problem of in-stent restenosis.