Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools.

An endoprosthesis device comprising a tubular structure having an outer surface and an inner surface such that the inner surface locates a lumen, and wherein the outer surface includes a microstructure pattern having hierarchical microstructures generating an adhesive effect to a target surface. The inner surface comprises a microstructure pattern that is superhydrophobic or oleophobic that is capable of being anti-fouling wherein the microstructure pattern of the inner surface comprises microridges. Additionally, the outer surface may include pores that fluidly connect the outer surface to the inner surface for transporting fluid from the target surface interface into the endoprosthesis lumen.

Embodiments of the present disclosure are related to devices and techniques for para-valve sealing of an expandable stent-valve implanted using a catheter. In some embodiments, a stent-valve is provided which comprises a seal sleeve/cuff containing material that swells when contacted by blood. A piercing tool may be included and used to permit a user to puncture the sleeve/cuff prior to introduction into a patient's body. In some embodiments, the sleeve/cuff has an integral tubular structure configured to withstand balloon expansion of the stent-valve during or after implantation. In some embodiments, the seal is provided as a separate component from the stent-valve.

A through-air bonded nonwoven fabric comprises a first surface and a second surface and a visually discernible pattern of three-dimensional features on one of the first or second surfaces. Each of the three-dimensional features define a microzone comprising a first region and a second region. The first and second regions have a difference in values for an intensive property, wherein in at least one of the microzones, the first region exhibits a Contact Angle of greater than 90 degrees, as measured by the Contact Angle Test Method, and wherein the second region exhibits a Time to Wick of less than 10 seconds, as measured by the Time to Wick Test Method.

A flexible intraocular lens including a reinforcing layer disposed on a sidewall of the intraocular lens is described. An example flexible intraocular lens includes a lens body and a reinforcing layer disposed thereon.

A method for preparing a biological material for implanting provides irradiating at least a portion of the surface of the material with an accelerated Neutral Beam.

A polymeric stent having a length, an outer surface and a cross-section. A lumen passes through the entire length, the lumen having a surface forming an equivalent diameter in the polymeric stent. The polymeric stent includes a first aqueous-swellable, biocompatible and biodegradable composition (e.g., polymer) having a thickness. The aqueous-swellable and biodegradable polymer retaining structural integrity for at least 1 hours up to thirty days when swollen and kept moist by a moist aqueous environment. Barrier layers of biodegradable polymer(s) may be used to prevent migration of liquids into the lumen.

A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.

A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.

An intraocular lens includes an annular housing coupled to a first window to form a lensing cavity. Disposed within the lensing cavity is two immiscible liquids, including a first liquid and a second liquid which form a meniscus at an immiscibility interface between the first liquid and the second liquid within the lensing cavity. The intraocular lens includes a flexible reservoir to store a variable portion of the first liquid. The flexible reservoir is disposed about at least a portion of a periphery of the annular housing. The intraocular lens also includes at least one channel linking the flexible reservoir to the lensing cavity to permit a transfer of the first liquid between the flexible reservoir and the lensing cavity. The transfer of the first liquid changes a curvature of the meniscus to adjust optical power of the intraocular lens.