Vascular filters and deflectors and methods for filtering bodily fluids. A blood filtering assembly can capture embolic material dislodged or generated during an endovascular procedure to inhibit or prevent the material from entering the cerebral vasculature. A blood deflecting assembly can deflect embolic material dislodged or generated during an endovascular procedure to inhibit or prevent the material from entering the cerebral vasculature.

Lens support structure for supporting an intraocular lens (IOL) is provided, the lens support structure being configured and operable to be securely implanted in a lens capsule of a human eye and hold the IOL in one of a plurality of positions, the support structure comprising a repositioning assembly configured and operable to be activated remotely by a remote energy source and controllably displace the IOL in at least one of directions along and around an optical axis of the IOL, thereby enabling moving the IOL between the plurality of positions. Lens control system is also provided, the control system comprising the lens support structure and a source energy for activating parts thereof. Intraocular lens system is also provided, the system comprising the lens support structure and a lens integrated therein.

Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.

Devices, systems, and methods for implanting a patient-specific prosthesis at a treatment site in a patient are disclosed herein. In some embodiments, a patient-specific prosthesis includes a tubular graft and a coupling member. A fenestration can be disposed in the tubular graft, the fenestration corresponding to a predicted branch blood vessel location. The coupling member can be disposed about the fenestration. The coupling member can include a coil configured to expand from a first configuration to a second configuration in response to the application of an expanding force. The coil can be configured to contract to a third configuration upon removal of the expanding force.

A valve-in-ring annuloplasty device according to the present technology includes a body coupled to an annuloplasty ring. The body is configured to align an artificial valve coaxially with the annuloplasty ring to reduce complications cause by misalignment of the artificial valve. A chamber wall, extending through the annuloplasty ring from a base portion configured to be attached to a valve annulus, is used to align the artificial valve during deployment. The chamber wall may include a plurality of struts configured to increase a rigidity of the chamber wall in the coaxial direction to ensure proper deployment of the artificial valve. The base portion may provide an increased suture area that decreases a likelihood for paravalvular leaking around the annuloplasty ring.

Provided is a stent that can be easily and reliably placed in a branched portion of a biological lumen. A stent is configured to be placed within a biological lumen and comprises: a first skeleton which is for placement within a first lumen of the biological lumen, and which is made of a wire material and formed into a tubular shape; and second skeletons which are for placement within a plurality of second lumens branched from the first lumen, and which are made of a wire material different from that of the first skeleton and whish are formed into a tubular shape. The plurality of second skeletons are provided so as to branch from one end section of the first skeleton and are engaged with each other at the branched portion.

A kit and method for reconstructing an Achilles tendon may include a first anchor member, a first flexible member configured to engage the first anchor member, a second anchor member, a second flexible member configured to engage the second anchor member, a first adjustable anchor assembly including a first outer member and a first inner member configured to axially translate within a first lumen of the first outer member in response to rotation of the first inner member relative to the first outer member, a second adjustable anchor assembly include a second outer member and a second inner member configured to axially translate within a second lumen of the second outer member in response to rotation of the second inner member relative to the second outer member, and a collagen implant configured to engage a surface of the Achilles tendon.

A modular IOL system including intraocular primary and secondary components, which, when combined, form an intraocular optical correction device, wherein the secondary component is placed on the primary component within the perimeter of the capsulorhexis, thus avoiding the need to touch or otherwise manipulate the capsular bag. The secondary component may be manipulated, removed, and/or exchanged for a different secondary component for correction or modification of the optical result, on an intra-operative or post-operative basis, without the need to remove the primary component and without the need to manipulate the capsular bag. The primary component may have haptics extending therefrom for centration in the capsular bag, and the secondary component may exclude haptics, relying instead on attachment to the primary component for stability. Such attachment may include actuatable interlocking members.

Methods for crimping a stent on an expandable member of a delivery catheter, and devices and methods for treating a bifurcation are disclosed. A method for crimping includes positioning a stent having a first portion and a second portion over the expandable member, and non-uniformly crimping the stent to the expandable member. The method can include routing an elongate shaft under the second portion of the stent and through the side hole so as to be routed external to the first portion. The stent second portion can be crimped so that the elongate shaft can be slidably disposed relative to the stent second portion prior to deployment of the stent.

A method for transcatheter delivery to a native heart valve needing replacement. A first component is attached to the native annulus upstream of the native leaflets maintaining native leaflet function, and is held to the native annulus by barbs that are activated by a torus balloon after the first component is fully expanded. The torus balloon can be implanted along with the support frame. A limiting cable restricts further expansion of the first component and holds a second component that contains the replacement leaflets.