A prosthetic heart valve can comprise a stent frame radially movable between a contracted configuration and a maximum expanded configuration. The stent assembly can comprise a plurality of longitudinally extending jack strut assemblies, wherein each jack strut assembly comprises a proximal jack strut comprising a distal surface, a distal jack strut comprising a proximal surface, and a jack screw connecting the proximal jack strut and the distal jack strut. The proximal surface of each distal jack strut does not contact the distal surface of each respective proximal jack strut when the stent assembly is in the contracted configuration. The proximal surface of each distal jack strut contacts the distal surface of each respective proximal jack strut when the stent assembly is in the maximum expanded configuration.

A prosthetic valve delivery device includes a handle and a delivery catheter. The delivery catheter includes a central elongate member extending from the handle and a proximal sheath configured to slide over and relative to the central elongate member. The proximal sheath is connected to a hollow helical strand, and the hollow helical strand is configured to rotate to retract the proximal sheath and expose at least a portion of the prosthetic valve.

An apparatus for use at a native valve of a heart of a subject comprises a tubular frame (30) circumscribing a longitudinal axis to define a lumen, a valve member (62) disposed within the lumen and coupled to the tubular frame, an outer frame (40), and a pin (50). The outer frame is composed of a shape-memory alloy. The tubular frame and the pin are composed of a material that is not the shape-memory alloy. The outer frame comprises a flange (42), defines an eyelet (44), and is disposed radially outward from the tubular frame. The pin defines a shaft (52) and a head (54), and couples the outer frame to the tubular frame. The head is disposed against the outer frame, radially outward from the eyelet, the shaft extends from the head through the eyelet to the tubular frame, and the shaft is welded to the tubular frame.

An orthopedic device for implanting between adjacent vertebrae comprising: an arcuate balloon and a hardenable material within said balloon. In some embodiments, the balloon has a footprint that substantially corresponds to a perimeter of a vertebral endplate. An inflatable device is inserted through a cannula into an intervertebral space and oriented so that, upon expansion, a natural angle between vertebrae will be at least partially restored. At least one component selected from the group consisting of a load-bearing component and an osteobiologic component is directed into the inflatable device through a fluid communication means.

A medical arrangement for introducing an object, such as an implant into an anatomical target position comprises a first introducer, a guide wire and a guiding catheter). The guide wire is configured to be introduced before the guiding catheter and object into or towards the anatomical target position. The guiding catheter is configured to be delivered into the position along the guide wire, after which the guide wire is configured to be retracted. The object is configured to be delivered inside the guiding catheter after the guide wire is retracted.

A medical arrangement for introducing an implant into an anatomical target position comprises a first introducer and a guide wire. The guide wire is configured to be introduced before the implant into or towards the anatomical target position. The implant is configured to be delivered along the guide wire into the anatomical target position. The guide wire is configured to be retracted after the implant has been introduced into said anatomical target position so that said object essentially maintains the shape taken when introduced into said anatomical target position.

An annuloplasty device is disclosed comprising first and second support rings having a coiled configuration, an elongate element to apply a force onto retention units and being movable between a first state and a second state, at least part of the first and second support rings comprises an interior channel to contain the elongate element, wherein, in the first state of the elongate element, the retention units have a retracted position, in which the retention units are arranged radially within an outer surface of the first and/or second support rings, wherein, in the second state of the elongate element, the retention units have an expanded position, in which the retention units protrude from the outer surface of the first and/or second support rings.

A frame for a prosthetic heart valve includes a plurality of strut members arranged to form an annular main body of the frame and coupled together by pivot joints. The main body of the frame is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration, and has an inflow end and an outflow end. The frame includes a plurality of leaflet clamps disposed on an exterior of the frame, each of the leaflet clamps including a pair of strut members pivotably coupled to the strut members of the frame, the leaflet clamps being movable between an open position corresponding to the collapsed configuration of the frame and a closed position corresponding to the expanded configuration of the frame. Motion of the frame between the collapsed configuration and the expanded configuration causes corresponding motion of the leaflet clamps between the open position and the closed position.

A shunt comprises a central flow portion configured to fit at least partially within an opening in a tissue wall. The tissue wall is situated between a first anatomical chamber and a second anatomical chamber and the opening represents a blood flow path between the first anatomical chamber to the second anatomical chamber. The central flow portion is further configured to maintain the blood flow path from the first anatomical chamber to the second anatomical chamber, prevent in-growth of tissue within the opening, and expand in response to expansion of the tissue wall.

An implantable device is disclosed. The device includes a leaflet frame subcomponent and an anchor frame subcomponent that are configured to be delivered in a series configuration and subsequently nested or telescoped in-situ.