Multilumen implant for application in human and animal vascular systems/bodies, with a substantially tubular element (1) divided into a proximal (2) and a distal section (3), and a fixation element (8) for the fixation of the proximal section (2) in a target vessel, wherein the tubular element (1) branches into two or more lumens (4, 5) in the distal section (3), with the fixation element (8) being at least one clamping ring (8) arranged on the outside of the proximal section (2) of the tubular element (1), and wherein the free end of the proximal section of the tubular element (1) is folded around the clamping ring (8) and embraces the clamping ring (8) in a pocket-like manner.

The present invention relates to biomaterial in the form of dispersion of cellulose nanofibrils with extraordinary shear thinning properties which can be converted into desire 3D shape using 3D Bioprinting technology. In this invention cellulose nanofibril dispersion, is processed through different mechanical, enzymatic and chemical steps to yield dispersion with desired morphological and rheological properties to be used as bioink in 3D Bioprinter. The processes are followed by purification, adjusting of osmolarity of the material and sterilization to yield biomaterial which has cytocompatibility and can be combined with living cells. Cellulose nanofibrils can be produced by microbial process but can also be isolated from plant secondary or primary cell wall, animals such as tunicates, algae and fungi. The present invention describes applications of this novel cellulose nanofibrillar bioink for 3D Bioprinting of tissue and organs with desired architecture.

Described herein are eye implants that can include a pressure-responsive material that can be capable of changing color in response to pressure exerted on it. Also described here are methods of implanting and using the eye implants described herein to monitor intraocular pressure in a subject. The pressure-responsive material can be used to diagnose and monitor human or animal subjects.

An animal headphone assembly for soothing a canine when the canine is exposed to distressing sounds includes a pair of headphones. Each of the headphones has a diameter sufficient to cover ears of a canine for wearing over each of a canine's ears. A plurality of straps is each coupled between each of the headphones to extend around the canine's head for retaining the headphones over the canine's ears. A sound unit is integrated into the headphones to emit sound outwardly therefrom. The sound unit stores a database comprising a plurality of musical songs to emit pleasing sounds into the canine's ears. Each of the musical songs includes concealed binaural beats to soothe the canine.

A link (1) for connecting two loops of a flexible tension-carrying construct (2, 2a). It solves the problem of providing effective means to connect two anchor points (7, 7a), typically on bones articulating at a joint by the flexible tension-carrying construct.

A surgical guidance system (SGS) for performing a cruciate pivot osteotomy in canines to treat cranial cruciate ligament disease. The SGS comprises a guide, a jig, and a plate. The guide is first placed over the tibia until it interacts with specific anatomical features of the tibia, thereby marking the proper position for the jig to be placed. After the jig has been secured, a blade defines an osteotomy within a proximal portion of the tibia. A portion of the jig is then cranially rotated providing a rotational correction of the proximal tibia. A compressive force is then applied to the osteotomy by the jig. Next the multiplane locking plate is placed over the osteotomy as dictated by the features of the jig. After initially securing the plate into its correct position, the jig is removed and the plate is then secured to the cranial surface of the tibia.

A sound-limiting device is provided, that includes an earplug body of a resilient elastomeric material, and that has a first portion whose shape corresponds generally to the shape of the vertical canal of a dog's inner ear, and a second portion sized and configured to flex through the elbow region of the dog's inner ear and into the horizontal canal. A spring element can be encapsulated in the first portion of the earplug body, and configured to apply a spring bias radially outward from an axis extending a length of the earplug body. The spring element is of a shape memory alloy having a transition temperature that is below a normal body temperature of a dog. The device can also include a sound conditioning element configured to produce a signal that is audible to an animal wearing the device.

An implantable medical device obtained by means of two-photon laser polymerisation of a resin to form a three-dimensional matrix, wherein: said three-dimensional matrix comprises a number of levels distributed in height; and said three-dimensional matrix comprises reference means designed to uniquely identify the height of each level from a pre-set reference, by means of a multi-photon fluorescence-excitation microscope; said implantable medical device being characterised in that said reference means comprise a solid having a cross section that varies with height.

The present invention provides a surgical treatment for a disordered knee in a dog, the disorder comprising a partially ruptured cranial cruciate ligament (CrCL), a fully ruptured CrCL, or a displaced patella. The methods of treatment include surgical transection of the tendon of the popliteal muscle, which reduces the in-toeing of the paw as it lands on the ground. In vitro experiments suggest that neutralization of this torque can reduce by several fold tensile forces in the CrCL or its replacement, as well as in its surrogate, a lateral suture placed extra-capsularly.

A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.