Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

Single-dose vials for liquid solutions (e.g., liquid medicaments) can be designed to be used in conjunction with a medication regimen. A single-dose vial may include a removable member that prevents a liquid solution from escaping, but also allows an individual (e.g., a patient or a medical professional) to readily administer the liquid solution. A single-dose vial could include one or more discrete capsules that include the same or different liquid solutions. For example, multiple capsules could be arranged within a vial so that different liquid solutions are simultaneously or sequentially ejected following removal of the removable member and application of pressure to the multiple capsules (e.g., due to the individual squeezing the vial). Multiple vials can also be connected to one another in a strip configuration, which allows the individual to more easily adhere to a medication regimen that requires multiple doses over a period of time.

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

An expandable intervertebral implant (10) includes superior (20) and inferior (30) bone contacting members and at least one vertical wire netting (50) interconnecting the superior and inferior bone contacting members. The superior and inferior bone contacting members include at least two bone contacting components interconnected via one or more lateral wire nettings such that the implant is vertically and laterally expandable in situ from a first insertion configuration to a second expanded configuration. The vertical and lateral wire netting are preferably constructed of a plurality of individual link members. The present invention also preferably relates to an associated method of manufacturing the intervertebral implant such that the intervertebral implant can be manufactured as an integral component or part.

An expandable intervertebral implant (10) includes superior (20) and inferior (30) bone contacting members and at least one vertical wire netting (50) interconnecting the superior and inferior bone contacting members. The superior and inferior bone contacting members include at least two bone contacting components interconnected via one or more lateral wire nettings such that the implant is vertically and laterally expandable in situ from a first insertion configuration to a second expanded configuration. The vertical and lateral wire netting are preferably constructed of a plurality of individual link members. The present invention also preferably relates to an associated method of manufacturing the intervertebral implant such that the intervertebral implant can be manufactured as an integral component or part.

Heart valve delivery systems and methods for providing a clinician with feedback during a stented prosthetic heart valve delivery procedure. Feedback is provided using piezochromatic indicators incorporated into elements of the delivery device, such as the handle assembly, shaft assembly and capsule to indicate when detrimental forces, or forces nearing those that are detrimental, are being applied to the delivery device during the prosthetic heart valve loading, delivery or deployment procedure. Other embodiments incorporate a feedback indicator to indicate that a delivery device has previously been used and is not in a new condition.

Single-dose vials for liquid solutions (e.g., liquid medicaments) can be designed to be used in conjunction with a medication regimen. A single-dose vial may include a removable member that prevents a liquid solution from escaping, but also allows an individual (e.g., a patient or a medical professional) to readily administer the liquid solution. A single-dose vial could include one or more discrete capsules that include the same or different liquid solutions. For example, multiple capsules could be arranged within a vial so that different liquid solutions are simultaneously or sequentially ejected following removal of the removable member and application of pressure to the multiple capsules (e.g., due to the individual squeezing the vial). Multiple vials can also be connected to one another in a strip configuration, which allows the individual to more easily adhere to a medication regimen that requires multiple doses over a period of time.

A medical device may include a shaft extending between a proximal end and a distal end. The shaft may include a lumen therein. The medical device may include a handle coupled to the proximal end of the shaft and may include a mode selector. The mode selector may be adapted to transition between a first mode and a second mode of the medical device. The medical device may further include a compressed fluid source. In the first mode, the compressed fluid source may be fluidly coupled with the shaft so as to impart a negative pressure in at least a portion of the lumen. In the second mode, the compressed fluid source may be fluidly coupled with the shaft so as to impart a positive pressure in the at least a portion of the lumen.

Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants.

This invention is related to a cartridge Injector System developed to be used for intraocular lens implantation, that enables the lens injection via a microsurgical incision in the eye and basically wraps the lens (L) by holding from the edges and provides the lens implantation with this method, also related with twisting body (7) keeping the lens in a closed environment.