Systems and methods for providing deeper knee flexion capabilities. In some instances, such systems and methods include a femoral knee replacement component that includes an articular surface, a first interior surface, and a second interior surface, wherein the first and second interior surfaces run substantially parallel to each other. In some cases, the articular surface includes an anterior condylar extension that is configured to replace an anterior articular cartilage of a femur such that the anterior extension is configured to terminate adjacent to a proximal limit of the anterior articular cartilage of the femur. Other implementations are also discussed.

The strength of bone implant attached to a bone is improved by using hybrid inserts which have stems and wings having bone ingrowth surface features and caps having outer surfaces of cured polymethyl methacrylate (PMMA). The stems and wings of the hybrid inserts are inserted into living bone and the bone implant is attached to the hybrid inserts with PMMA cement. Over time, the bone grows into the bone ingrowth surface features. The bone ingrowth strengthens the bonding of the hybrid inserts and the bone implant with the bone over time. The hybrid inserts increase the shear, tensile and torque strength of the bone implants. Bone inserts that do not have ingrowth surface features loosen over time.

The modular mould (1) for forming an orthopaedic spacer made of medical cement defines a moulding cavity delimited by a moulding surface (3, 3, 3) and configured for impressing a predetermined shape on said medical cement and realising said orthopaedic spacer. The mould (1, 1) comprises a first sector (7a, 7a, 7a), defining a first portion of said surface, and a second sector (7b, 7b) defining a second portion of the surface, the first and the second portion of the surface being variable, so as to obtain spacers having variable dimensions.

A knee spacer device configured to be implanted temporarily at the joint area between the tibia and femur of a patient to replace an infected joint prosthesis and to maintain the size or spaces of the patient's joint area before implanting a new prosthesis includes a tibial unit and a femoral unit.

An implantable modular spacer device to treat an infected articular seat includes a stem element, a head or ball element, and coupling elements between the stem element and the head that include a plurality of elongated teeth, placed at pre-established distances from each other, and a plurality of housing seats for the teeth. An implantable spacer device to treat a bone seat or joint seat or for the two-step treatment of infections of joint prostheses includes a joint component adapted to be inserted in an articular zone of the patient and having an external surface, a stem component adapted to be implanted in a bone or in a residual bone bed of a preceding joint prosthesis, and adjustable connection elements, wherein at least part of the external surface of the first portion of the stem component and at least part of the external surface of the joint component define a contact surface with the bone tissue or adapted for coupling with the bone tissue. The connection elements are placed between the joint component and the stem component to adjust the distance thereof, and the contact surface in the joint component and/or in the stem component has a plurality of recesses or housing a filling material that includes a pharmaceutical or medical substance, wherein the plurality of recesses affects or is substantially placed along the entire contact surface or in proximity thereto.

A central inflatable distractor and a perimeter balloon are inserted into the disc space in uninflated configurations. The central inflatable distractor is then expanded, thereby distracting the vertebral endplates to the controlled height of the central inflatable distractor. The perimeter balloon is then inflated with a curable substance. The perimeter balloon expands as it is filled with the curable substance and conforms to the void remaining in the disc space around the central inflatable distractor, thereby creating a horseshoe shape. Once the flowable material in the perimeter balloon has cured, the central inflated distractor can be deflated and removed. The remaining void (or inner space) is then packed with graft for fusion.

A scaffold (12) for tissue engineering comprises an inner portion (14), an outer portion (16), and a base portion (22) connecting the inner portion and the outer portion. The inner portion (14) comprises a channel (18) surrounded by a first set of one or more walls. The outer portion (16) comprises a second set of one or more walls. The portions are arranged such that the second set of one or more walls substantially surrounds the first set of one or more walls with a spacing between the first and second sets of walls defining a cavity (20) between the inner portion (14) and the outer portion (16). The inner portion (14) and the outer portion (16) may have different shapes; and/or the scaffold (12) may further comprise a filler material in the cavity (20) defined between the inner and outer portions.

A cement mold assembly configured to form a temporary implant for use in delivering antibiotics to an infected site can includes a first mold and a second mold. The first mold can have an open end and an inner wall. The first mold can define a tibial component forming cavity including a platform forming cavity and a stem forming cavity. The second mold can have a body portion configured to be slidably and progressively receivable by the inner wall into the tibial component forming cavity in a direction toward the closed end. Progressive advancement of the second mold into the tibial component forming cavity urges cement within the tibial component forming cavity against the body portion and the inner wall to form a unitary tibial component having a tibial tray portion formed by the platform forming cavity and a stem portion formed by the stem forming cavity.

A cranial implant for access to a cerebral cortex includes a window member shaped and dimensioned for positioning within a dural defect to provide access through the dura such that access to the cerebral cortex is provided in a location under study. An implant body is provided having a geometry that substantially conforms to a resected portion of a patient's anatomy to which the implant body is to be secured.

A modular spacer device for a knee joint includes a tibial element adapted to be constrained to an end of the tibial bone and a femoral element adapted to be constrained to an end of the femoral bone and to be articulated on the tibial element. The tibial element has first and second surfaces opposite to each other, and the femoral element has first surface and second surfaces opposite to each other. The first surface of the femoral element is convex and laterally has a curved, ammonite-shaped contour with a curvature radius that increases starting from a rear section with a curvature radius R1, a first central section having a curvature radius R2, a second central section having a curvature radius R3, and a front section having a curvature radius R4, with R1R2R3R4.