A nonwoven fabric comprises a first surface and a second surface, and at least a first visually discernible zone on at least one of the first surface and the second surface. The first visually discernable zone has a pattern of three-dimensional features, each of the three-dimensional features defining a microzone comprising a first region and a second region. The first and second regions have a difference in values for an intensive property. The first visually discernible zone has a visually sharp pattern defined by a periodic Haralick Wave Response, as determined according to the Haralick Maximum Contrast Test Method defined herein.

A method for making nonwoven fabric. The nonwoven fabric can include three-dimensional features that define a microzone comprising a first region and a second region. The first and second regions can have a difference in values for an intensive property. The nonwoven further has a plurality of apertures, wherein at least a portion of the aperture abuts at least one of the first region and the second region of the microzone.

A method for making nonwoven fabric. The nonwoven fabric can include three-dimensional features that define a microzone comprising a first region and a second region. The first and second regions can have a difference in values for an intensive property. The nonwoven further has a plurality of apertures, wherein at least a portion of the aperture abuts at least one of the first region and the second region of the microzone.

The present disclosure relates to the technical field of bone repair and provides a berberine/mineralized collagen-based composite membrane as well as a preparation method and an application thereof. The composite membrane of the present disclosure includes a berberine nanofiber membrane and a mineralized collagen membrane disposed on a unilateral surface of the berberine nanofiber membrane. In the present disclosure, the mineralized collagen with biomimetic mineralization capacity is combined with a Chinese materia medica monomer, berberine, the resulting bilayer composite membrane has a better effect on promoting osteogenesis; in addition, a novel dosage form of berberine is constructed. The present disclosure employs an electrospinning method to prepare a berberine nanofiber membrane, the berberine nanofibers are received by the mineralized collagen membrane, or after the berberine nanofiber membrane is obtained, a mineralized collagen membrane is prepared by applying on the surface of the berberine nanofiber membrane.

A nonwoven fabric comprises a first surface, a second surface, and a visually discernible pattern on at least one of the first and second surfaces. The visually discernible pattern has a regular, repeating pattern of three-dimensional features. Each of the three-dimensional features define a microzone comprising a first region and a second region. The first and second regions having a difference in values for an intensive property. The first surface has a TS7 value in the range of about 1 dB V.sup.2 rms to about 15 dB V.sup.2 rms. The second surface has a TS7 value in the range of about 1 dB V.sup.2 rms to about 15 dB V.sup.2 rms. A ratio of the TS7 value of the first surface to the TS7 value of the second surface is in the range of about 1 to about 3.

A nonwoven fabric comprises a first surface, a second surface, and a visually discernible pattern on at least one of the first and second surfaces. The visually discernible pattern has a regular, repeating pattern of three-dimensional features. Each of the three-dimensional features define a microzone comprising a first region and a second region. The first and second regions having a difference in values for an intensive property. The first surface has a TS7 value in the range of about 1 dB V.sup.2 rms to about 15 dB V.sup.2 rms. The second surface has a TS7 value in the range of about 1 dB V.sup.2 rms to about 15 dB V.sup.2 rms. A ratio of the TS7 value of the first surface to the TS7 value of the second surface is in the range of about 1 to about 3.

An apparatus has a particle and/or fiber-making device and a foraminous endless belt extending in a longitudinal travel direction. A pair of horizontally spaced end rollers between which the belt is stretched horizontally receive fibers or particles from the device. A rotatable support roller between the end rollers directly engages and supports the belt, extends a full width of the belt, and has a diameter of less than 200 mm.

An apparatus has a particle and/or fiber-making device and a foraminous endless belt extending in a longitudinal travel direction. A pair of horizontally spaced end rollers between which the belt is stretched horizontally receive fibers or particles from the device. A rotatable support roller between the end rollers directly engages and supports the belt, extends a full width of the belt, and has a diameter of less than 200 mm.

A method of electrospinning (40) is provided, and an electrospinning device (1; 30). The method comprises (i) holding (41) a liquid comprising a polymer melt or a polymer solution in a container (2), (ii) letting out (42) a stream of the liquid from the container through at least one nozzle (3), (iii) creating (43) a voltage difference between the nozzle (3) and a collecting surface (4), (iv) collecting (44) electro spun material coming from the nozzle (3) so as to form a fibrous structure (8) on the collecting surface (4), and (v) directing (45) a laser beam (13) towards the collecting surface (4) so as to locally remove a part of the fibrous structure (8).

A method of creating a soft and lofty continuous fiber nonwoven web is provided. The method includes providing molten polymer to a spinneret defining a plurality of orifices, and flowing a fluid intermediate the spinneret and a moving porous member. The moving porous member is positioned below the spinneret. The method includes using the fluid to draw or push the molten polymer, in a direction that is toward the moving porous member, through at least some of the plurality of orifices to form a plurality of individual continuous fiber strands. The method includes depositing the continuous fiber strands on the moving porous member at a first location to create an intermediate continuous fiber nonwoven web, and removing and/or diverting some of the fluid proximate to the first location to maintain loft and softness in the deposited intermediate continuous fiber nonwoven web.