Surgical suturing constructs, suture anchor assemblies, and methods of tissue fixation are disclosed. The suturing construct includes a bumpy suture. A suturing construct may include one or more small loops on a distal end. A suturing construct may include a splice terminating into a tapered portion/region at a proximal end. A bumpy suture of a suturing construct may form a knotless, closed, self-locking loop around tissue.

A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. The apparatus includes a member to pull the soft tissue implant into a femoral tunnel. The member includes a suture having first and second ends which are passed through first and second openings associated with the longitudinal passage to form a pair of loops. A collapsible tube is positioned about the suture. Application of tension onto the suture construction causes retraction of the soft tissue implant into the femoral tunnel and the collapse of the tube to form an anchor.

A system for making a surgical suture having a reformed tip includes a receiver die having a top surface, a bottom surface, and an elongated channel formed in the top surface that extends between first and second ends of said receiver die. The elongated channel includes a suture channel having a first end and a second end, a first sloping surface that extends downwardly between the first end of the suture channel and the first end of the receiver die, and a second sloping surface that extends downwardly between the second end of the suture channel and the second end of the receiver die. The system includes an upper die having a top surface and a bottom surface that opposes the top surface of the receiver die. The system has an open die position in which the bottom surface of the upper die is spaced away from the top surface of the receiver die and a closed die position in which the bottom surface of the upper die is in contact with the top surface of the receiver die. A cutting element is coupled with the receiver die and the upper die.

Methods and systems for braiding sutures and the resulting constructs are disclosed. The sutures can have alternating bifurcated and non-bifurcated lengths. The sutures can have looped-ends, with both ends of the loop having contiguous braiding with the adjacent body or remainder of the suture. Braiding machines can have one or more bifurcating bars that can controllably obstruct or allow passage of the shuttle and carriers of the braiding machine. The controllable bifurcating bars can result in u-turns in the shuttle and carrier paths, such as a path encircling a horngear adjacent to the bifurcating bar, or passage of the shuttle and carrier across the bifurcating bar.

A method of suturing includes: (1) wrapping a first segment of a suture through a traction loop; (2) pulling the traction loop and the first segment through an opening in a suture lock; (3) continuing to pull the traction loop such that a second segment of the suture extends through the opening, wherein the second segment has a greater denier than the first segment such that the second segment more nearly fills an entire dimension of the opening than the first segment; and (4) locking the suture in place with the second segment in the opening.

The invention relates to a method for forming a barbed suture (10) comprising: a) producing a knit by knitting together i) a set of chain stitch yarns (1) producing chain stitches and ii) a set of monofilament weft yarns completing weft stitches with at least one of said chain stitches, thereby producing at least one weft stitched chain stitch (6), b) cutting the knit along the warp direction on both sides of said weft stitched chain stitch, so as to isolate said weft stitched chain stitch from the rest of the produced knit, the chain stitch yarn of said at least one weft stitched chain stitch forming the elongate body (9) of the barbed suture and the monofilament cuts (7) extending from said weft stitches of said one weft stitched chain stitch forming the barbs (8) of said barbed suture.

Resorbable implants, coverings and receptacles comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing molding, pultrusion or other melt or solvent processing method. The implants, or the fibers preset therein, may be oriented. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings, receptacles and implants described herein, may be made from meshes, webs, lattices, non-wovens, films, fibers, foams, molded, pultruded, machined and 3D printed forms.

A method for processing amniotic membrane to create a suture including cutting dried amnion layer into a designated final strip size, the cut and dried strips are twisted into a thread-like structure, interlacing the thread-like structures and drying the interlaced thread-like structure to form the suture.

A strand that can be used to support repair of a soft tissue injury is disclosed. The strand comprises high strength collagen fibers and high strength biocompatible fibers, such as polyethylene fibers arranged into a strand that can be used as part of a suture or other scaffold for the repair of joints and soft tissues, such as ligaments and tendons. The fibers may be over-braided around a central core, which is itself comprised of two or more fibers. The high strength collagen fibers are strong enough to withstand the stresses imposed by industrial braiding machines and processes.

Absorbable composite medical devices such as surgical meshes and braided sutures, which display two or more absorption/biodegradation and breaking strength retention profiles and exhibit unique properties in different clinical settings, are made using combinations of at least two types of yarns having distinctly different physicochemical and biological properties and incorporate in the subject construct special designs to provide a range of unique properties as clinically useful implants.