The disclosure provides systems and methods for neuromodulation using a housing that at least partially contains a stimulator assembly, wherein the stimulator assembly is configured to generate vibration by mechanical oscillation and/or using a sound wave; and wherein the vibration generated by the stimulator assembly is configured to therapeutically treat the subject by stimulating one or more nerves when the housing is placed in proximity to or on a skin surface of a subject.

A wearable stimulator device can be used to treat nausea and vomiting resulting from pregnancy, gastroparesis, virtual reality use, motion sickness, chemotherapy, and post-surgical nausea and vomiting, or other conditions by stimulating the P6 point of a user's forearm. A method of treating nausea includes monitoring one or more physiological parameters of a user via a wearable device, for example a smartwatch. Based on the one or more physiological parameters, the P6 point of the user's forearm can be stimulated for a predetermined time, for example via vibrational stimulation effected via a smartwatch or other wearable device. Data regarding the user's physiological parameters, stimulation sessions, and user-provided input regarding treatment efficacy and user symptoms can be collected and analyzed at scale to develop improved treatment regimes, for example modifying stimulation waveforms and/or timing, and identifying physiological parameters useful for predicting the onset of nausea.

An ultrasonic medicine application device that strongly promotes medicine absorption, having a housing, a control panel and a circuit board inside the housing, a medicine supply mechanism and an ultrasonic massage mechanism on a bottom surface of the housing. The ultrasonic massage mechanism has a base panel having massage projections, and also an electrical ultrasonic vibration element, which drives the projections make high frequency ultrasonic vibration. The medicine supply mechanism is positioned between the ultrasonic massage mechanism and the circuit board, and is configured to supply medicine towards the ultrasonic massage mechanism.

A device including a semi-rigid shell forming an external surface with at least part of the shell adapted to contact tissue of a body cavity. The shell includes a treatment band formed around the shell, a first portion forming a rounded end of the device that is distal to the treatment band, and a second portion formed around the circumference of the shell and located proximal to the treatment band. The device further includes a vibration mechanism configured to case the shell to vibrate, a sensor configured to provide sensor data upon contact with the tissue, and a processor configured to receive the sensor data and to use the sensor data to produce parameters of the tissue.

Provided is an electric field-vibration generating transducer having a piezoelectric material of a high degree of displacement, and a manufacturing method thereof. The electric field-vibration generating transducer lowers the cost of production through miniaturization simultaneously with realizing excellent generating characteristics of the electric field-vibration generating transducer based on high efficiency and low voltage driving because the piezoelectric material of the high degree of displacement (high strain piezoelectrics) having a high piezoelectric constant (d.sub.33=1,000 to 6,000 pC/N), a high dielectric constant (K.sub.3.sup.T=6,000 to 15,000) as well as a low dielectric loss (tan δ<2%) is applied thereto, so the electric field-vibration generating transducer may accelerate the movement of a material, a chemical action, and a biological reaction, and may be applied to a medical device for the purpose of treatment for tumors aimed at human bodies and animals.

Use of ultrasound beams to unlock the perception of mid-air tactile stimuli on hairy skin by using acoustic streaming is described. Such acoustic streaming is directional, more focused than fan and air-puff devices, doesn't require the use of cumbersome attachments, fast since it can be generated at a distance with the speed of sound, and can be used in a complementary fashion with vibrotactile mid-air stimulation deriving from the same hardware. Further proposed is a way to modulate the thermal perception of the mid-air tactile stimuli without the need for a thermal source or wearables. The effect of acoustic streaming and its thermal modulation may be combined for the accurate elicitation of affective touch sensations.

A handheld focused extracorporeal shock wave therapy (f-ESWT) device includes a plurality of piezoelectric elements, a power supply circuit, and a plurality of driver circuits. The piezoelectric elements are each configured to generate an individual shock wave. The power supply circuit is configured to output a first DC voltage and a second DC voltage. The first DC voltage greater than the second DC voltage. The driver circuits are each operably connected to the first DC voltage, the second DC voltage, and to a corresponding piezoelectric element of the plurality of piezoelectric elements. Each driver circuit includes a switching element electronically configurable in an open state and in a closed state. When the switching element is in the open state, the first DC voltage and the second DC voltage are applied to the corresponding piezoelectric element to pre-charge the corresponding piezoelectric element with a DC pre-charge voltage having a first polarity.

A medicine application device with ultrasonic massage enabling concentrated supply of medicine, including a medicine concentrated supply device, at least one ultrasonic massage mechanism, a medicine supply pipe and power cables. The ultrasonic massage mechanism has a shell, a base panel having massage projections, and an electrical ultrasonic vibration element; the medicine concentrated supply device has a housing, a control panel, a circuit board, and a medicine supply device. The medicine application device provides high frequency ultrasonic massage and applies medicinal therapy to patients.

A cold plasma system and method for treating a region of a biological surface is presented. In one embodiment, the system includes: a housing; an air conduit within the housing; a first electrode configured proximately along the air conduit; a second electrode configured proximately along the air conduit and opposite from the first electrode; and a source of alternating current (AC) electrically connected with the first electrode. The source of alternating current is configured to generate cold plasma in the air conduit.

A cosmetic treatment device includes a treatment surface that faces a human body, at least three head portions, and an oscillation portion. The head portions are arranged at a spacing with each other on the treatment surface, each head portion including an ultrasonic vibrator and being configured to vibrate together with the ultrasonic vibrator. The oscillation portion is configured to cause the ultrasonic vibrators to vibrate.