Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings and receptacles are made from meshes, webs, lattices, non-wovens, films, fibers, and foams, and contain antibiotics such as rifampin and minocycline.

Provided is a method of manufacturing a dental cord. The method including: producing a spinning solution by dissolving a fiber-moldable hydrophobic polymer material in a solvent; spinning the spinning solution to obtain a polymer nanofiber web composed of nanofibers and including three-dimensional micropores; laminating the polymer nanofiber web to obtain a polymer membrane; slitting the polymer membrane to obtain a nanofiber tape yarn; hydrophilic-treating the nanofiber tape yarn to obtain a hydrophilic-treated nanofiber tape yarn; plying and twisting the hydrophilic-treated nanofiber tape yarn with a covered yarn to obtain a nanofiber multiple yarn; and impregnating the nanofiber multiple yarn with a hemostatic agent.

The present invention relates to a method for manufacturing gold thread with no drawing-induced inconsistency, and gold thread manufactured by the method, wherein: gold thread is manufactured by spirally twisting together a plurality of gold rods, each having a relatively smaller thickness than the prior art gold rod, whereby the gold thread ensures sufficient rigidity, and thus inconsistency of the gold thread, induced by drawing of gold, can be eliminated; and the gold thread formed by spirally twisting together a plurality of gold rods has an increased surface area, as compared to the conventional gold thread having the same diameter, and thus can alleviate skin aging and improve antibacterial properties by increasing the frictional force with the skin.

The present invention refers to yarns made of hollow trilobal cross section filaments, comprising from 90 to 99% of polypropylene, and between 1 and 10% of other polyolefin resins, for the application on dental floss. This invention additionally refers to the production process of the yarns made of hollow trilobal cross section filaments. This invention additionally refers to dental floss comprising hollow trilobal cross section filaments, and the use of hollow trilobal cross section filaments for the manufacture of dental floss. The yarn described in this invention has linear density or title in the range from 400 to 1200 dtex, and it is twisted with a twist level from 10 to 160 twists per meter.

The present invention provides an artificial blood vessel that can achieve a balance between cell penetration efficiency and crush resistance and can regenerate a blood vessel at very high efficiency. Provided is an artificial blood vessel having a tubular shape, including: a foam containing a bioabsorbable material; a reinforcement A containing a bioabsorbable material; and a reinforcement B including threads containing a bioabsorbable material, the foam being reinforced with the reinforcements A and B, wherein the reinforcement A is a non-woven fabric, a film, or a weft-knitted, warp-knitted, or woven fabric made of knitted or woven fibers, the reinforcement B includes monofilament threads each having a cross-sectional diameter of 0.1 mm or more and 1 mm or less, the reinforcement B includes a winding portion having a helical shape, a ring shape, or an X shape and a warp thread portion stretched in a direction parallel to a longitudinal direction of the artificial blood vessel, and the artificial blood vessel is a composite including the reinforcement A and reinforcement B inside the foam.

An implant includes a frame, and a textile mounted on the frame. The textile includes fibers formed from a mixture of a polymer and an additive molecule. The additive molecule includes a polyurethane backbone and one or more fluorinated end-groups at at least one end of the backbone. Other embodiments are also described.

Provided is yarn for a cell culture scaffold. The yarn for a cell culture scaffold according to an exemplary embodiment of the present invention includes slitting yarn produced by cutting a compressed nanofiber web to a predetermined width. Accordingly, by creating microenvironments suitable for migration, proliferation and differentiation of cells, cell viability may be enhanced and cells may be three-dimensionally proliferated. In addition, a scaffold according to the present invention has a mechanical strength sufficient for prevention of disruption of the scaffold which occurs during cell culture, such that cells may be stably proliferated. Further, the scaffold according to the present invention uses slitting yarn formed of the compressed nanofiber web, thereby having pores with various sizes, and therefore cell proliferation and cell viability may be enhanced by creation of an extracellular matrix-like environment.

Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators. The coverings and receptacles are made from meshes, webs, lattices, non-wovens, films, fibers, and foams, and contain antibiotics such as rifampin and minocycline.

Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate torsional actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize coiled yarns/polymer fibers and can be either neat or comprising a guest. In some embodiments, the torsional fiber actuator includes a first polymer fiber (exhibiting a first polymer fiber diameter) and a torsional return spring in communication with the first polymer fiber. The first polymer fiber is configured to include a first plurality of twists in a first direction to produce a twisted polymer fiber. The first polymer fiber is further configured to include a plurality of coils in the twisted polymer fiber in a second direction each coil having a mean coil diameter. In some embodiments, the torsional nanofiber actuator includes a first carbon nanofiber yarn (having a yarn diameter) and a torsional return spring in communication with the first carbon nanofiber yarn. The first carbon nanofiber yarn includes a plurality of twists in a first direction to produce a twisted carbon nanofiber yarn. The first carbon nanofiber yarn further includes a plurality of coils in the twisted carbon nanofiber yarn, with each coil having a mean coil diameter greater than the yarn diameter.

Ophthalmic suture materials made from biocompatible and biodegradable polymers with high tensile strength for use in drug delivery, methods of making them, and method of using them for ocular surgery and repair have been developed. The suture materials are made from a combination of a biodegradable, biocompatible polymer and a hydrophilic biocompatible polymer. In a preferred embodiment the suture materials are made from a poly(hydroxyl acid) such as poly(1-lactic acid) and a polyalkylene oxide such as poly(ethylene glycol) or a polyalkylene oxide block copolymer. The sutures entrap (e.g., encapsulate) one or more therapeutic, prophylactic or diagnostic agents and provide prolonged release over a period of at least a week, preferably a month.