A cryotherapy system can include an erectable apparatus that can be at least partially inflatable, and configured to extend at least partially around a treatment area adapted to contain at least both vaporized cryogen and at least a portion of a user's body to be cryogenically treated; and a cooling system configurable to provide vaporized cryogen to the treatment area.

A cold chamber is provided with a walk-in interior space that includes a wall cladding. The wall cladding is arranged in front of a wall of the cold chamber in such a way that the wall cladding and the wall form a cavity. The wall is heatable at least partially.

A soaking device and methods of using are used to cool and/or to heat a face of a person for a purpose of inducing a desired and/or intended outcome in that person. The cooling and/or the heating of the face may be sufficient to induce the desired and/or the intended outcome in that person. The desired and/or intended outcome may relate to: release of at least one type of neurotransmitter; trigeminal nerve stimulation; (indirect) vagus nerve stimulation; transdermal drug delivery; bypass of the blood-brain-barrier (BBB); aesthetic medicine; cardiovascular; dermatological; ears, nose, and throat (otolaryngological); ophthalmological; neurological; psychological; endocrinological; and/or rheumatological benefits to that person. At least one step of the method may include receiving at least some of the face within an immersion-liquid for at least a minimum amount of time while the immersion-liquid is within a temperature-range and while the immersion-liquid is within the soaking device.