Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.

Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.

A method for treating cancer is described using combination therapies comprising the use of hyperbaric oxygen with histone deacetylase inhibitors, with and without glycolytic therapies. The patient is subjected to a hyperbaric environment of substantially pure oxygen. A predetermined dose of one or more HDACI substances is administered to the patient. In addition, glycolitic inhibitors may also be administered. Dosages, pressures, and durations are selected as described herein to have a therapeutic effect on the patient.

A medical treatment system including a treatment chamber, a source of an aqueous mist containing a medication, a source of an oxygen-enriched gas, and a control system adapted to alternately surround a human body part with a mist containing a medication and the oxygen enriched gas, which can be used to treat various skin disorders including infected lesions, bacterial infections such as acne (i.e. Propionibacterium acnes), fungal infections such as Athelete's foot (i.e. fungal genus Trichophyton), conditions associated with hair loss including alopecia as well as ulcerations and frostbite resulting from poor circulation. A method of treating skin disorders is also disclosed, that includes providing a mist containing a medication and enriched oxygen gas to the site being treated as well as providing oxygen to the patient during treatment.

The subject matter of the invention is a therapeutic device in the form of a cylindrical chamber which comprises a hyperbaric chamber, LED matrices (5) and inductive coil rings (10, 11, 12, 13), constructed in one inseparable set in the form of a chamber of 200-280 cm in length and diameter of the round cylinder (70-130 cm).

The present invention includes an apparatus for transdermal treatments comprising: an openable enclosure for a subject in communication with three or more sources of treatment modalities selected from: a source of ozone; a source of steam, a source of CO.sub.2/Carbonic Acid; a source of Far Infrared; and a source of pulsed electromagnetic fields (PEMF), wherein each of the three or more sources is in communication with an interior of the openable enclosure to treat the subject transdermally.

A system (5) for generating a gaseous mixture for an enclosure (7) for treatment of a wound (3), comprising a generator (11) for generating the gaseous mixture and for delivering said gaseous mixture to the treatment enclosure (7) at a defined flow rate, the generator (11) of the gaseous mixture being designed to vary a molar fraction of dioxygen of said delivered gaseous mixture and to vary a molar fraction of water vapour of said delivered gaseous mixture, a control unit (39) which serves for controlling the delivered gaseous mixture and is provided with a processor (41) for receiving information relating to a pressure (P) inside the treatment enclosure (7) and/or designed to determine a flow rate of said gaseous mixture to be delivered in the treatment enclosure (7) in order to obtain an internal target pressure, the target pressure being defined by a time variation function of the pressure between a minimum pressure, corresponding to an ambient pressure outside the treatment enclosure (7), and a maximum pressure.

The present invention provides an apparatus for producing medical foam for wound care or hair stimulation. The apparatus includes a foam generation unit having a fluid reservoir, a fluid delivery line and a foam generation tip. The apparatus also includes a compressed gas unit having at least one container of compressed gas, a source of electric power, and a gas regulator valve. A supply of wound care or hair stimulating solution is communicably connected to the foam generation tip such that when the apparatus is operated medical foam is produced by the foam generator tip.

A therapeutic device for treating conditions of a user's nasal cavities, sinuses, and/or ear canals includes a housing which the user may hold to apply the therapeutic device to the user, the housing including an inlet that allows air to enter the therapeutic device. An acoustic vibrator located within the housing provides an acoustic vibration to the user, and a power supply located within the housing provides power to the acoustic vibrator. A mask is connected to the housing and includes a nasal interface that is appliable around the nose of the user. A valve of the mask opens to allow the user to breathe through the inlet and closes to prevent the user from exhaling through the inlet. The mask further includes a diaphragm and a nasal cavity in which a user's nostrils are located when the nasal interface is applied to the user.

Embodiments of the present invention are directed to devices, systems and methods adapted for implementing intermittent displacement of blood to mitigate peripheral nerve neuropathy such as that induced by chemotherapeutic agents (i.e., chemotherapy-induced neuropathy (CIN)) that are administered to a patient. Such devices, systems and methods advantageously provide for precise, uniform and controlled blood flow occluding (and optionally blood displacing) compression along irregular surfaces of an appendage of a patient. Such precise, uniform and controlled blood occluding compression is imparted upon the epidermal and dermis skin layers within the aforementioned areas of a patient's extremities to decrease the time that free nerve endings located in the epidermal and encapsulated nerve endings located in the dermis skin layers are exposed to nerve damaging chemotherapy chemicals, thereby substantially decreasing CIN caused by prolonged exposure to such chemicals.