A medicine application device with ultrasonic massage enabling concentrated supply of medicine, including a medicine concentrated supply device, at least one ultrasonic massage mechanism, a medicine supply pipe and power cables. The ultrasonic massage mechanism has a shell, a base panel having massage projections, and an electrical ultrasonic vibration element; the medicine concentrated supply device has a housing, a control panel, a circuit board, and a medicine supply device. The medicine application device provides high frequency ultrasonic massage and applies medicinal therapy to patients.

A skin treatment device and a method to cleanse and balance pH value of skin. The skin treatment device includes a nozzle to be directed into contact with the skin of a subject. A vacuum pump may be operably coupled to the nozzle for generating a suction force of the nozzle to evacuate impurities from the skin. A liquid replenishing assembly may be operably coupled to the nozzle for atomizing liquid at a pre-defined pH value. The liquid from the liquid replenishing assembly may pass into the nozzle based on the pre-defined pH value. The first control valve may be connected to an outlet of the vacuum pump and an outlet of the liquid replenishing assembly for communication with the nozzle.

Systems and methods for nasal irrigation are provided in which a nasal irrigation device includes a source of saline solution, an effluent receptacle, a nasal interface, a vacuum source, a fluid passageway to communicate the source of saline solution with the effluent receptacle through the nasal interface and a nasal cavity of the user, and a switch and valve assembly for selectively controlling the vacuum source and flow of the saline solution through the fluid passageway. The saline solution source bottle is disposed relative to the device to provide gravitational inducement of saline solution to the nasal interface in engagement to the device user's nostrils. A combination of the gravitational inducement and the relative vacuum from an effluent receptacle generates a fluid flow for irrigating, cleansing and massaging the nasal cavity and ostia of a user. The entire device is assembled as a hand-held device for convenient lifting and disposal against the user's nostrils.

The present disclosure relates to extracellular vesicles (EVs) that are capable of targeting a cell in the CNS of a subject. Also provided herein are methods for producing the EVs and methods for using the EVs to treat and/or prevent diseases or disorders of the CNS (e.g., neurological disorders).

Disclosed are a sexual stimulation method and a sexual stimulation apparatus. The method includes obtaining a video segment, wherein the video segment includes a sexual stimulation scenario; parsing the video segment and generating a chronological sexual stimulation parameter set corresponding to the video segment; and playing, by a video play device, the video segment; and synchronously performing, by a sexual stimulation apparatus, a multi-dimensional stimulation operation according to the chronological sexual stimulation parameter set.

A mask, according to an embodiment, comprises: a first wiring disposed on a first base layer; a piezoelectric element disposed on the first wiring; a second wiring disposed on the piezoelectric element; a second base layer disposed on the second wiring; a protective layer disposed between the first and second base layers and surrounding the first wire, the second wire, and the piezoelectric element; and a control unit which controls a driving frequency of the piezoelectric element. The control unit controls the driving frequency of the piezoelectric element in a frequency band defined as a first range, and the temperature of the piezoelectric element changes by means of the control of the driving frequency of the control unit.

Methods and devices for treating a targeted tissue including a skin or a lip and more particularly methods and devices that enhances absorption of treatment media into tissue for cosmetic and therapeutic purposes.

Systems include a receiving port configured to receive a cartridge configured to store a material capable of being aerosolized, a sensor configured to generate one or more measurements based on ambient conditions of a housing, an aerosolizer configured to aerosolize the material in response to receiving a signal, and a controller comprising one or more processors configured to generate the signal provided to the aerosolizer, and further configured to control operation of the aerosolizer via the signal.

A therapeutic device, for human hair and skincare, comprises a gripping unit a functional unit including a first functional module and a second functional module, the first functional module including a first plate and a second functional module including a second plate, wherein a second surface of the second plate is oriented in an opposite direction to a first surface of the first plate, a plurality of teeth oriented in the direction of the orientation of the first surface, the plurality of teeth including a plurality of respective primary Light Emitting Diodes (LEDs), a plurality of secondary LEDs provided on the second plate and oriented in the direction of the orientation of the second surface and a sensor unit configured to determine hair distribution data on a body portion of a user.

A vibration therapy device that includes a housing that includes a handle portion, a head portion, and a module seat defined on the head portion, an electrical source, a motor positioned in the housing, a switch for activating the motor, a push rod assembly operatively connected to the motor, a reciprocating attachment removably secured to a distal end of the push rod assembly and configured to provide a first type of therapy, and a therapy module removably secured to the module seat and configured to provide a second type of therapy.