A medicine-taking detection system is provided that includes an ingestion device 1 and a detection device that detects taking of the ingestion device. The ingestion device includes a medicine, a signal transmission unit that transmits a first signal, a signal reception unit that receives a reflected signal of the first signal transmitted from the signal transmission unit, and a secondary battery that supplies power to the signal transmission unit and the signal reception unit. The signal transmission unit is configured to, when the signal reception unit receives the reflected signal, transmit a second signal including information on a signal intensity of the reflected signal, and the detection device receives the second signal and detects the taking of the ingestion device based on the information on the signal intensity of the reflected signal.

Modular smoking devices that vaporize certain materials, such as tobacco or cannabis are disclosed. The technology provides for intelligent ignition, combustion, or vaporization of given material at the appropriate temperatures that prevent generation of harmful and unwanted byproducts. According to one embodiment, the modular smoking device comprises a self-contained combustion chamber to hold the material, a combustion mechanism integrated with the self-contained combustion chamber, and an energy source, such as a rechargeable battery, to power the combustion mechanism. The combustion mechanism is configured to provide targeted combustion of the material, where the active ingredients generated upon the combustion are consumed by inhaling a smoke or vapor resulting from the combustion or vaporization. The self-contained combustion chamber includes a lighterless combustion mechanism such as a piezoelectric lighter or a lighter sold under TESLA COIL LIGHTERS® that is designed to arc an electric discharge through the material in the self-contained combustion chamber.

A method and system of forming a pharmaceutical dosage form within a portion of a blister packaging. The method includes the steps of providing a blister packaging for the dosage form with depressions. A predetermined amount of a drug-containing powder material comprising drug-containing particles is deposited into a substantially uniform powder layer within the depressions. A binding liquid is then deposited in a pattern on the powder layer within the depressions, to bind the particles of the powder layer and form an incremental wetted layer, Excess solvent in the binding material can be removed to form an incremental bound layer. These steps are repeated in sequence at least one or more times to form the pharmaceutical dosage form within the blister packaging.

A medicine removal detection system is provided that includes a medication device and a storage member in a sheet shape storing the medication device. The medication device includes medicine, a secondary battery, and a signal transmission unit that transmits a signal indicating a state of the secondary battery. The storage member includes the electric current supply line for supplying an electric current to the secondary battery of the medication device, and is configured such that a supply environment of an electric current to the secondary battery changes when the medication device is taken out. The signal transmission unit transmits a signal indicating a state change of the secondary battery based on a change in the supply environment of an electric current to the secondary battery of the storage member.

Provided are methods of producing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of determining the purity of a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of distributing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of assessing suitability of migalastat hydrochloride for medical use.

A medication packaging and dispensing system is provided. The system may include a plurality of medication booklets containing medication and a tray that is configured to retain the medication booklets. Each medication booklet may include a sequential tab assembly of pull tabs that aligns with a plurality of front cutouts and a plurality of back cutouts. This alignment configuration facilitates dispensing the medication from the medication booklet. The tray may include a riser that extends from a bottom wall of the tray at an oblique angle, and a first guide panel including a plurality of linear stops. The oblique angle may correspond to a pitch of the first guide panel. The riser and the plurality of linear stops may cooperate to maintain the medication booklets in a staggered configuration that is substantially parallel to the bottom wall of the tray. The system may further include a container for retaining the tray.

The present invention provides a coating material that can improve gravure printing characteristics of the printing surface of a printing substrate to favorably transfer an ink fed in the cell of a gravure printing roll to the printing surface of the printing substrate, thereby achieving the beautiful gravure printing. The coating material of the present invention is a coating material for forming a surface layer serving as a printing surface on a printing substrate to which gravure printing is to be applied, and the coating material is characterized by including a pigment including an inorganic particulate and a skin layer that is formed on a surface of the inorganic particulate and includes an organic compound.

A portable, reusable dispensing assembly having multiple operating modes is provided. The assembly includes a housing having a compartment which is refillable with an elongated medication strip having a plurality of dosage form packages spaced apart along a longitudinal axis of the strip. A bi-directional, electromechanical actuator advances a first end of the strip from the compartment to a dose-ready area in the housing in a dispensing mode of the assembly and loads the strip into the compartment in a loading mode of the assembly. An actuator controller is configured to receive power and direction command signals to controllably supply DC power of a desired polarity to the actuator to control the operating mode of the assembly.

The present disclosure relates to wireless medication blister pack assembly and to a blister pack attachment to be secured to a blister pack assembly. The attachment an electronic card housing for receiving an electronic card which includes electronic components such as card connectors, and a locking system which is configurable between a locked configuration and a releasing configuration. In the locked configuration, the blister pack assembly and the electronic card are connected, with sheet connectors provided on the blister pack assembly and the card connectors being in electronic communication. Such electronic communication allows the electronic components to detect whether a given blister has been detached from the blister pack assembly. In the releasing configuration, the electronic card and the blister pack assembly can be removed from the blister pack attachment, so as to allow the electronic card to be reused with a replacement blister pack assembly.

A multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber holds an item to be dispensed and is surrounded by a flange. A closure member, in the form of a respective portion of a frangible cover sheet, is adhesively secured to the flange of each compartment unit. Each closure member includes plural tamper-evident cuts therein located adjacent respective corners of the closure member to initiate a tear upon attempted removal of the closure member from the flange of its associated compartment unit.