To provide a medication storage cell that can be easily opened by a person who cannot dexterously move his or her fingertips. A small-medication storage cell (12) is provided with an accommodating section (20) and an interlocking piece (22). The accommodating section (20) has an outlet for a medication (100). The outlet (30) is formed using a sheet (60) provided with an interlocking piece, and a cover sheet (62). The interlocking piece (22) has a base section (40) and a tip end section (42). At least a part of the base section (40) is separated from the surface of the accommodating section (20). The tip end section (42) is fastened to the accommodating section (20) in a bent state so that the cover sheet (62) and the sheet (60) provided with an interlocking piece close the outlet (30).

The present invention relates to a stable pharmaceutical composition comprising a combination of chlordiazepoxide hydrochloride and clidinium bromide and one or more pharmaceutically acceptable excipients, wherein the composition is in the form of solid oral dosage forms like capsule and sachet. The technical challenges like undesirable impurities in dosage form were successfully controlled by using: a) low moisture excipients; and b) formulation development under controlled temperature and controlled humidity conditions. The formulations as per the present invention are stable and exhibit desired pharmaceutical technical attributes like assay and dissolution. The prepared formulations are useful for the treatment of gastrointestinal disorders and various other therapeutic indications as described herein.

Embodiments are directed to apparatuses, methods and systems for tracking usage of an item. In one scenario, a microcontroller is configured to send a periodic signal over electrical traces that are distributed over an item to determine whether a change in electrical throughput has occurred in a trace. Upon determining that such a change has occurred, an indication is generated that describes the type of usage that occurred and the time at which the use occurred. An indication of the type of usage and the time of occurrence is then provided to specified recipients. Apparatuses for tracking such usage include a battery, a microprocessor, a transmitter and capsules for storing the controlled substances. Each capsule has an electrical trace extending through at least some of the capsule. The microprocessor is configured to determine, using the electrical traces, which capsules have been opened by identifying which traces have been broken.

A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.

A compartmentalized container loading and management system for loading compartmentalized containers, such as blister cards. A single system may be utilized to hand-load many different types of blister cards having different numbers of wells arranged in different patterns. Systems of the types described herein may include a docking station, a container locator, and a controller. The docking station may include visible information locations which provide visible information proximate wells of a docked blister card to indicate the well which should be loaded. The visible information locations may be changed to match the number, arrangement and pattern of the wells. A container locator may locate the blister card with wells at known positions of the docking station so that visible information may be associated with each well. A controller may control the visible information locations to provide visible information matching the pattern of the wells of each blister card.

A medicament dispensing container comprises a first wall and a second wall defining a cavity therebetween. At least one member is connected to at least one of the walls and is disposable in the cavity. The at least one member defines at least one dose receptacle configured for disposal of at least one dose of at least one medication. The at least one member includes indicia relating to a medication regimen comprising the at least one medication. The walls are movable between a medication accessible configuration and a tamper resistant configuration. Systems and methods of use are disclosed.

A pharmaceutical product can be distributed to respective patients in a plurality of jurisdictions. First and second jurisdictions can have different labeling requirements than each other. A plurality of inner containers each store the pharmaceutical product, the pharmaceutical product being in a dosage form and in a package approved by each jurisdiction of the plurality. An inner container can be sealed within a first outer container including labeling required by the first jurisdiction and not required by the second jurisdiction. Another inner container can be sealed within a second outer container including labeling required by the second jurisdiction and not required by the first jurisdiction. The sealed first and second outer containers respectively can be distributed to the first and second jurisdictions.

The present invention features a compound of formula I: ##STR00001##
or a pharmaceutically acceptable salt thereof, where R.sub.1, R.sub.2, R.sub.3, W, X, Y, Z, n, o, p, and q are defined herein, for the treatment of CFTR mediated diseases, such as cystic fibrosis. The present invention also features pharmaceutical compositions, method of treating, and kits thereof.

A blister pack having a backing having a first side and an opposing second side. Each of the first and second side is flat or planar. The blister pack can also include a cover having a first side and an opposing second side. At least a portion of the second side of the cover is adhered to the first side of the backing to form a sealed package for containing product. The cover can include at least one blister. The blister pack can also include an active member positioned within each blister. Each active member can be in the form of a ring with an opening extending therethrough or a depression formed therein.

A medication information and storage device that provides easy, on-hand, transportation and storage of medication and information regarding a health condition for which the medication may, in an emergency, stop or limit certain, possibly life-threatening, symptoms. The device includes a card with printed information, such as symptoms, treatments, and how to best take accompanying medication, and a cavity containing medication disposed in a corner of the card. In use, the device is carried upon a person, such as in a wallet, retrieved and read by a person when experiencing a health condition, and opened to provide medication for the health condition, if the person believes after reading the information that taking the medication may help.