A pouch comprises a film including (i) a fold defining a fold plane and a first marginal edge portion of the pouch, (ii) a first side transverse to the fold plane, and (iii) a second side opposite the first side and transverse to the fold plane. A fitment of the pouch includes a port and a base. The base defines a mid-portion engaging the fold at the fold plane, a first side located on one side of the mid-portion, and a second side located on an opposite side of the mid-portion relative to the first side. The first and second sides of the base are transverse to the fold plane, and are engaged with the first or second sides of the film, respectively. The base or film overlaps the other and defines an overlapping region. The base and film are sealed to each other within the overlapping region and form a fluid-tight seal that extends about the port.

A medical infusion apparatus with infusion bottle having inbuilt balloon is disclosed, wherein a polyvinyl chloride plastic capsule or spherical balloon is built in the production of infusion bottle, glass bottle, polypropylene (PP) plastic bottle, polyvinyl chloride (PVC) plastic capsule, non-polyvinyl-chloride polyolefin infusion soft bag, and the PVC plastic capsule or spherical balloon is elastic, uniformly distributed with 6 pinholes on a surface thereof, has a volume of 10% of a liquid capacity of the infusion bottle or infusion bag, and is disposed in the infusion bottle or infusion bag in a fixed state or an unfixed natural state; the infusion bottle or infusion bag is injected with a base liquid during production, and also the plastic capsule or spherical balloon is naturally filled with the base liquid.

A pouch for transporting and/or processing a biopharmaceutical fluid, the pouch comprising a flexible wall, the flexible wall comprising a shape memory material being adapted to change shape when induced by an external stimulus, so that the pouch can be alternately in a collapsed state and in an unfolded state, the wall of the pouch in the unfolded state delimiting a closed internal cavity adapted to contain the biopharmaceutical fluid.

A container for transporting and/or processing a biopharmaceutical fluid, the container comprising a wall, the wall comprising a shape memory material being adapted to change shape when induced by an external stimulus, so that the container can be alternately in a collapsed state and in an unfolded state, the wall of the container in the unfolded state delimiting an internal cavity adapted to contain the biopharmaceutical fluid.

Device for receiving and draining a high quantity of biopharmaceutical fluid under pressure includes an inner bag, having an inner container for receiving the fluid and provided with a filling port, a drain port, a filling tube having a filling inlet for connection to a filling line, a drain tube having a drain outlet for connection to a drain line, an outer container in which the bag is placed, a compression chamber between the outer container and the bag, an injection port for injecting pressurized draining gas into the chamber, sealed bushings passing through the container via the filling and drain tubes, the deformation capacities of the bag and container being such that, when the draining gas is injected into the chamber, the bag is compressed and the biopharmaceutical fluid is emptied. The outer container includes a receptacle forming the outer chamber, the tubes passing therethrough via permanently fixed connections.

A medicament container including at least one sidewall and an extension is provided. The extension may be rigid in comparison to sidewalls that form the volume of the container. The extension may extend substantially into the volume of the container to a central region of the container. The container may include one or more ribs formed in the sidewalls to provide structural rigidity to the sidewalls.

A syringe adapter is used for connecting a dosing syringe to a container in order to take up a fluid. The syringe adapter has a fluid delivery channel for creating a flow connection between the inside of the container and the inside of the dosing syringe. At least one ventilation channel of the syringe adapter is used for creating an air connection between the inside of the container and the container surroundings. In at least one of the channels a non-return valve is arranged, which allows the passage of media in an open position and in a closed position closes the channel. This results in a syringe adapter which has improved handing and in particular provides sufficient dosing precision.

A container unit may be used to facilitate administrations of multiple medicinal fluids to a patient. A container unit may include a first container, a second container, and a carrier which holds the first container and the second container stationary relative to each other. The carrier may include a lip configured to engage a pooling device to secure the container unit to the pooling device. The carrier may also include a slot configured to engage an insert on the pooling device to guide the container unit as the container unit is secured to the pooling device. The carrier may also include a first portion and second portion with different shapes that are complementary to a shape of a port on the pooling device. The carrier may also include an extension which extends in a direction away from one of the first container to a level at least even with a stopper disposed in the first container. The container unit may include a lid including at least one rotation inhibitor configured to inhibit rotation of the lid about at least one axis. A plurality of container units may include container units having different volume containers while maintaining a congruent interface portions.

A container consisting of plastic material that is produced using the blow, fill and seal method and the filler material of which, enclosed by a container wall (15, 20), can be autoclaved, is characterized in that at least one shaping means (19, 21, 23, 25, 29, 33) is provided in the container wall (15, 20), which ensures, despite a low relative air volume in the container, that when administering the filler material by infusion the container wall (15, 20) collapses at least partially reducing the volume, without aeration of the container.

Disclosed are sterile aqueous choline salt compositions, their preparation, and methods of use. Also disclosed are methods to treat choline deficiency, intestinal failure associated liver disease (IFALD), and fatty liver disease. Additionally disclosed is a method of synthesis of choline salts.