The invention relates to a tamper evident plastic closure for necked vials, for holding a plug in a mouth of a vial, comprising: a tubular locking body configured to be locked at the neck of the vial, and a cap coupled with the tubular locking body. The tubular locking body comprises a retaining member for retaining the plug, a central opening being formed in the retaining member for providing access to the inside of the vial via the plug. The cap comprises a disc-shaped cover and a coupling portion, for coupling the cap with the tubular locking body by positive-fit engagement. The coupling portion comprises at least one frangible portion each configured such that at least one indicator member remains as a tamper evidence at a rim of the central opening of the tubular locking body after removal of the cap from the distal end of the tubular locking body by irreversibly breaking the annular frangible portion for providing access to the inside of the vial via the plug.

In general, adaptive responses from smart packaging of drug delivery absorbable adjuncts and methods of using smart packaging of drug delivery absorbable adjuncts are provided.

An apparatus for inspection of IV bags includes a base having a working surface. A conveyor is raised above the working surface with conveyor supports and includes a plurality of bag clips, each adapted to hold one of the IV bags in an inverted position at one of a plurality of workstations. A controller moves the conveyor such that the bag clips each move from one workstation to the next at set intervals. A loading workstation places one of the IV bags into one of the bag clips. A bubble mitigation station agitates a fluid within the IV bag to dislodge any air bubbles. Two particle agitation stations agitate the fluid and any debris particles. An inspection station includes a backlighting apparatus, a camera, a display, and a rejection chute leading to a disposal receptacle. An unloading workstation unloads IV bags that have passed inspection.

An apparatus for inspection of IV bags includes a base having a working surface. A conveyor is raised above the working surface with conveyor supports and includes a plurality of bag clips, each adapted to hold one of the IV bags in an inverted position at one of a plurality of workstations. A controller moves the conveyor such that the bag clips each move from one workstation to the next at set intervals. A loading workstation places one of the IV bags into one of the bag clips. A bubble mitigation station agitates a fluid within the IV bag to dislodge any air bubbles. Two particle agitation stations agitate the fluid and any debris particles. An inspection station includes a backlighting apparatus, a camera, a display, and a rejection chute leading to a disposal receptacle. An unloading workstation unloads IV bags that have passed inspection.

A bag for containing a biopharmaceutical product includes at least one fluid input/output port and a measurement opening remote from the fluid port. A probe holder port has a body with an axial through-bore and a peripheral collar with a second fastening zone and defining a fastening plane. A contact probe, extending in the axial through-bore, is assembled on the probe holder port, has an active measurement end portion in contact with the product, and has an end portion opposite the end portion. The probe holder port includes a transition portion between the body and the collar, which extends between a radially central end portion of the collar and a first axial end portion of the body. The first axial end portion is the axial end portion closest to the radially central end portion of the collar. The first axial end portion is disposed on the outer side relative to the fastening plane, and the active measurement end portion is axially disposed on the outer side relative to the fastening plane.

A bag for containing a biopharmaceutical product includes at least one fluid input/output port and a measurement opening remote from the fluid port. A probe holder port has a body with an axial through-bore and a peripheral collar with a second fastening zone and defining a fastening plane. A contact probe, extending in the axial through-bore, is assembled on the probe holder port, has an active measurement end portion in contact with the product, and has an end portion opposite the end portion. The probe holder port includes a transition portion between the body and the collar, which extends between a radially central end portion of the collar and a first axial end portion of the body. The first axial end portion is the axial end portion closest to the radially central end portion of the collar. The first axial end portion is disposed on the outer side relative to the fastening plane, and the active measurement end portion is axially disposed on the outer side relative to the fastening plane.

A characteristic of a blood product in a blood product container is determined. Using a smartphone, an image is acquired of a blood bag or tubing of the blood product container disposed in front of the smartphone. The image is processed using a processing circuit of the smartphone or a remote computer in wireless communication with the smartphone. The processing identifies a characteristic of the blood product from the image. A visual notification is generated on a display of the smartphone of the identified characteristic of the blood product.

A characteristic of a blood product in a blood product container is determined. Using a smartphone, an image is acquired of a blood bag or tubing of the blood product container disposed in front of the smartphone. The image is processed using a processing circuit of the smartphone or a remote computer in wireless communication with the smartphone. The processing identifies a characteristic of the blood product from the image. A visual notification is generated on a display of the smartphone of the identified characteristic of the blood product.

An injectable medication tab used to track expiration dates has an informative tab, a release string, an adhesive liner, and a quick release fastener. The informative tab provides visually accessible information about a bottle to which the injectable medication tab is attached. An expiration information portion of the informative tab protrudes from the exterior surface of the bottle after being opened. The adhesive liner is superimposed onto a mounting surface of the informative tab and attaches the informative tab to the bottle. The quick release fastener is a coupling mechanism that connects between an edge of the informative tab and the release string. The release string forms a detachable connection holding the expiration information portion against the bottle until the bottle is opened. Once opened, the expiration information section to protrudes from the bottle until the expiration information is recorded and the medical information portion is adhered to the bottle.

Packaging for a pharmaceutical product and a method of validating pharmaceuticals is disclosed. The packaging comprising a cavity; and validation circuitry comprising: a sensor adapted to output a signal in response to detecting a vapour in the cavity; and a detection circuit adapted to output an indication when the signal indicates a predefined vapour signature.