The production of a protein free synthetic polyisoprene which has both low levels of chemical impurities and good physical properties has yet to be realized. It has now been envisioned that the use of neodymium catalyzed polyisoprene will offer the combined advantages of both a clean, as well as, high cis-1,4 polymer. Synthesis of polyisoprene rubber using a neodymium based catalyst system is described. Characterization of the material shows the absence of an ultra high molecular weight fraction and the presence of very high cis-1,4-microstructure. Gum stock and black filled compound studies comparing neodymium polyisoprene with natural rubber, titanium polyisoprene, and lithium polyisoprene have been performed. Results indicate that polyisoprene rubber synthesized using a neodymium catalyst system (NdPI) has similar stress-strain and tear properties as synthetic titanium polyisoprene. Analysis of residual volatile, extractable, and oligomer levels indicates NdPI is indeed a clean source of high cis synthetic polyisoprene.

Apparatus and methods provide for a feeding bottle. According to embodiments described herein, a feeding bottle may include a container and a one-piece nipple assembly. The one-piece nipple assembly may include a ring substrate encompassed by a dome overmold with a nipple head. The nipple head and dome overmold may include a texture gradient and variable wall thickness to simulate a human breast. The interior of the nipple assembly 104 may additionally include an internal flow assist mechanism for assisting the fluid flow while the nipple head is bitten or pulled.

A teat for a drinking bottle has a nipple opening in the form of a slit arrangement. The slit arrangement has end portions which comprise curved paths. These curved paths resist tearing.

The invention relates to a multi-angle cup for feeding liquid food to a patient, the cup including, a body including a wall and an exit channel extending at an angle from the wall. A mouth part is also included, extending from the angled exit channel and an inclined angle to enable the patient to be fed liquid food in a controlled manner to the posterior aspect of the tongue through use of a bulb with a hole and valve arrangement. The multi-angle feeding cup enables feeding at substantially any angle of tilt of the cup, and the flow of the liquid food is controlled by the mouth piece. The invention also relates to methods of use and a method of testing.

The present invention relates to a method and device for collection of oral fluids comprising the use of a sealed evacuated sample container.

A nipple for use with an infant drinking cup is disclosed herein. The nipple comprises a domed portion having a central region and an inner surface, a teat portion radially offset from the central region, and a radially-outer wall. The radially-outer wall is joined to the domed portion at a joining location and comprises an inner fluid-flow surface, defining a fluid flow direction. A region of the inner surface of the domed portion at the joining location is substantially parallel to said fluid flow direction, or the inner fluid-flow surface of the teat portion extends radially outwardly, away from said region of the inner surface of the domed portion at the joining location.

The invention relates to an infant feeding assembly comprising a feeding bottle and a sealed cup holding a single serve of infant formula to be mixed with water. The bottle comprises a cup holder, a teat, a mounting ring, a water fill opening and a closure device. The cup holder is adapted to hold the cup, in an opened condition. The teat has a dome shaped base and a spout. The mounting ring releasably mounts the teat onto the cup holder. According to the invention, the water fill opening, through which a mixing cavity of the feeding bottle can be filled with water while the opened cup is held by the cup holder and the teat is mounted on the cup holder, is provided in the cup holder and/or in the mounting ring and/or in the teat. The cup and the teat at least partially define the mixing cavity.

The disclosure relates to a container having a multi-axial rotation assembly that facilitates a distribution of liquid at a variety of angles.

A infant bottle provides a timer to alert the user when an hour has elapsed. The infant bottle provides an endcap with a ring of LED lights around the base of the bottle, and a recessed button in the center of the bottom surface. Pressing the button once activates a one-hour timer. When the hour expires, the LED lights flash on and off until the button is pressed twice. Pressing the button twice at any time deactivates the timer. The endcap is easily removed for the purpose of placing the bottle in a dishwasher for cleaning.

The subject matter of this specification describes, among other things, devices and processes for providing measured doses of oral medication to patients, such as infants or other vulnerable patients.