Patent classifications
D01D5/0076
THREE DIMENSIONAL ELECTROSPUN BIOMEDICAL PATCH FOR FACILITATING TISSUE REPAIR
A three-dimensional electrospun biomedical patch includes a first polymeric scaffold having a first structure of deposited electrospun fibers extending in a plurality of directions in three dimensions to facilitate cellular migration for a first period of time upon application of the biomedical patch to a tissue, wherein the first period of time is less than twelve months, and a second polymeric scaffold having a second structure of deposited electrospun fibers. The second structure of deposited electrospun fibers includes the plurality of deposited electrospun fibers configured to provide structural reinforcement for a second period of time upon application of the three-dimensional electrospun biomedical patch to the tissue wherein the second period of time is less than twelve months. The three-dimensional electrospun biomedical patch is sufficiently pliable and resistant to tearing to enable movement of the three-dimensional electrospun biomedical patch with the tissue.
Electrospinning device and method
An electrospinning device (1; 30) is provided comprising: a container (2) for holding a liquid comprising a polymer melt or a polymer solution; a nozzle (3) arranged to outlet a stream of the liquid from the container; a collecting surface (4) for collecting electro spun material coming from the nozzle during an electrospinning process so as to form a fibrous structure (8) on the collecting surface (4); a voltage supply system (5) arranged to create a voltage difference between the nozzle and the collecting surface (4), one or more electrostatic emitters (10; 38) arranged to locally distribute positive and/or negative ions onto the fibrous structure, and one or more rotatable bodies (6; 36) arranged to cause the collecting surface (4) to face the nozzle (3) and the electrostatic emitters (10; 38) in turn.
Method for preparing quantum rod/polymer fiber membrane by using electrospinning technique
Disclosed is a method for preparing a quantum rod/polymer fiber membrane by using electrospinning technique. The method comprises the following steps: (1) preparing a quantum rod solution; (2) preparing a polymer solution, and adding the quantum rod solution obtained in step (1) into the polymer solution so as to form an electrospinning precursor solution with a volume concentration of the quantum rods of 5%-80%; and (3) adding the electrospinning precursor solution into an electrospinning device, regulating the voltage of a generator and the receiving distance, and then performing electrospinning to prepare the quantum rod/polymer fiber membrane. By adjusting the concentration of the quantum rod solution and parameters in the electrospinning process, the method realizes directional arrangements of the quantum rods in the electrospinning process, thereby obtaining the quantum rod/polymer fiber membrane with high degree of polarization performance.
METHODS AND SYSTEMS FOR PRODUCING BEADED POLYMERIC FIBERS WITH ADVANCED THERMOREGULATING PROPERTIES
A network of microfibers are fabricated with a core-shell construction from sustainable materials, where the core includes a phase-change material, such as coconut oil, and the shell includes a biomass, such as cellulose. The microfibers are made via a wet-wet electrospinning process utilizing a coaxial spinneret with an inner conduit and an outer conduit. The biomass and the phase-change material are coaxially extruded into a coagulation bath including a mixture of ethanol and water. The collected microfibers exhibit a beaded structure of PCM aggregates and biomass connecting regions between the aggregates and are effective to aid in the thermoregulation of the immediate environment surrounding the network. The microfibers are suitable for use in a variety of sustainable products such as wearable thermoregulating textiles, wall/ceiling panels, insulation, packaging material, and more.
BIOMEDICAL PATCHES WITH ALIGNED FIBERS
A structure of aligned (e.g., radially and/or polygonally aligned) fibers, and systems and methods for producing and using the same. One or more structures provided may be created using an apparatus that includes one or more first electrodes that define an area and/or partially circumscribe an area. For example, a single first electrode may enclose the area, or a plurality of first electrode(s) may be positioned on at least a portion of the perimeter of the area. A second electrode is positioned within the area. Electrodes with rounded (e.g., convex) surfaces may be arranged in an array, and a fibrous structure created using such electrodes may include an array of wells at positions corresponding to the positions of the electrodes.
RADIALLY CROSS-ALIGNED NANOFIBER MEMBRANE
A method for controlling fiber cross-alignment in a nanofiber membrane, comprising: providing a multiple segment collector in an electrospinning device including a first and second segment electrically isolated from an intermediate segment positioned between the first and second segment, collectively presenting a cylindrical structure, rotating the cylindrical structure around a longitudinal axis proximate to an electrically charged fiber emitter; electrically grounding or charging edge conductors circumferentially resident on the first and second segment, maintaining intermediate collector electrically neutral; dispensing electrospun fiber toward the collector, the fiber attaching to edge conductors and spanning the separation space between edge conductors; attracting electrospun fiber attached to the edge conductors to the surface of the cylindrical structure, forming a first fiber layer; increasing or decreasing rotation speed of the cylindrical structure to alter the angular cross-alignment relationship between aligned nanofibers in adjacent layers, the rotation speed being altered to achieve a target relational angle.
KINK-RESISTANT ELECTROSPUN FIBER ASSEMBLIES AND METHODS OF MAKING THE SAME
Systems and methods of fabricating corrugated electrospun fiber assemblies are disclosed herein. The method can include placing an electrospun fiber scaffold on a corrugation rod, wherein the corrugation rod comprises a helical structure; applying a monofilament fiber about the electrospun fiber scaffold and the corrugation rod from a dispenser as the dispenser is translated longitudinally and the corrugation rod is rotated such that the monofilament fiber is wrapped about the electrospun fiber scaffold at a defined threads per inch (TPI) to form a wrapped electrospun fiber assembly; and longitudinally compressing the corrugated electrospun fiber assembly until it has been compressed from a first length to a second length to form the corrugated electrospun fiber assembly. The corrugated electrospun fiber assemblies can be kink-resistant as compared to conventional electrospun fiber scaffolds. The corrugated electrospun fiber assemblies can be used in, for example, biological applications within a subject.
ELECTROSPINNING HEAD, ELECTROSPINNING APPARATUS, AND CLEANING METHOD OF ELECTROSPINNING HEAD
According to an embodiment, an electrospinning head includes a nozzle and an uneven surface. The nozzle is made from an electrically conductive material, and a flow path is formed inside the nozzle. On the outer surface of the nozzle, an ejection port capable of ejecting a material liquid supplied to the flow path is formed. The uneven surface is formed in the vicinity of the projection port on the outer surface of the nozzle, and an uneven shape of the uneven surface is formed around the entire circumference of the circumferential direction of the nozzle and is along the extending direction of the flow path.
System and Method for Creating and Object with a Conduit with Particular Vascular Applications
According to an embodiment of the disclosure, a method of creating an object with a conduit is disclosed. A material is deposited on a sacrificial collector; and, the sacrificial collector is then removed to create the object with the conduit. Both the object and the sacrificial collector can approximate the shape of desired blood vessel. The method can also include a 3-D printing of the desired shape of the mold and utilization of Gallium as the sacrificial collector. The sacrificial object is created by insertion of the gallium in the mold. After removal of the gallium from the mold, fibers are electrospun onto the gallium. The gallium is removed through melting—leaving a scaffold, the object with the conduit. In addition to the gallium, an extra sacrificial layer of a water-soluble material may be utilized.
METHOD FOR MANUFACTURING POROUS ANTI-ADHESIVE FILM
A method for manufacturing a porous anti-adhesive film is provided, which includes the steps of providing an electrospinning solution and performing an electrospinning process by using the electrospinning solution to form the porous anti-adhesive film The electrospinning solution includes a polymer material and a solvent. The solvent is selected from the group consisting of acetone, butanone, ethylene glycol, hexafluoroisopropanol (HFIP), isopropanol, deacetylated chitosan (DAC), N,N-dimethylformamide (DMF), dimethylacetamide (DMAC), dimethyl sulfoxide (DMSO), and ether.